Apokyn and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apokyn (apomorphine hydrochloride) and Flonase (fluticasone propionate). Common drug interactions include fall among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Apokyn and Flonase. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Apokyn?

Apokyn has active ingredients of apomorphine hydrochloride. eHealthMe is studying from 5,284 Apokyn users. Check the latest studies of Apokyn.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

25 people who take Apokyn and Flonase together, and have interactions are studied.

What are the common drug interactions of Apokyn and Flonase, by gender? *:

female:

Fall
Dyskinesia (abnormality or impairment of voluntary movement)
Alopecia (absence of hair from areas of the body)
Drug ineffective
Muscular weakness (muscle weakness)
Swelling face
Hallucination, visual (seeing things that aren't there)
Peripheral swelling
Somnambulism (sleep walking)
Hallucination (an experience involving the perception of something not present)

male:

Dizziness
Fall
Flushing (the warm, red condition of human skin)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Unresponsive to stimuli
Urinary tract infection
Vomiting
Back pain

What are the common drug interactions of Apokyn and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Injection site pruritus (severe itching at injection site)
Insomnia (sleeplessness)

50-59:

Dehydration (dryness resulting from the removal of water)
Insomnia (sleeplessness)
Unresponsive to stimuli
Dementia (madness)
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Speech disorder

60+:

Fall
Dyskinesia (abnormality or impairment of voluntary movement)
Nausea (feeling of having an urge to vomit)
Hallucination (an experience involving the perception of something not present)
Malaise (a feeling of general discomfort or uneasiness)
Peripheral swelling
Somnolence (a state of near-sleep, a strong desire for sleep)
General physical health deterioration (weak health status)
Hyperhidrosis (abnormally increased sweating)
Infection

What are the existing conditions these people have? *

Parkinson's Disease: 12 people, 48.00%
Dyskinesia (abnormality or impairment of voluntary movement): 9 people, 36.00%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 20.00%
Delusion (a false belief or opinion): 3 people, 12.00%
Stress And Anxiety: 2 people, 8.00%
Pain: 2 people, 8.00%
Neuropathy Peripheral (surface nerve damage): 2 people, 8.00%
Muscle Tightness: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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