Augmentin and Wellbutrin sr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Wellbutrin sr (bupropion hydrochloride). Common drug interactions include arthralgia among females and pain in extremity among males.
The phase IV clinical study analyzes what interactions people have when they take Augmentin and Wellbutrin sr. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.
What is Augmentin?
Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.
What is Wellbutrin sr?
Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.
53 people who take Augmentin and Wellbutrin sr together, and have interactions are studied.

What are the common drug interactions of Augmentin and Wellbutrin Sr, by gender? *:
female:
- Arthralgia (joint pain)
- Asthenia (weakness)
- Asthma
- Diarrhoea
- Drug ineffective
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Nausea (feeling of having an urge to vomit)
- Pyrexia (fever)
male:
- Pain in extremity
- Cardiac murmur (an heart sound in valve abnormality)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
- Back pain
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthropathy
- Bone disorder
- Cardiomegaly (increased size of heart than normal)
- Compression fracture (fracture due to pressure caused by injury)
What are the common drug interactions of Augmentin and Wellbutrin Sr, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Dental caries
- Emotional distress
- Gallbladder disorder
- Granulocytopenia (lack of granulocyte)
- Injury
- Vomiting
30-39:
n/a
40-49:
- Fatigue (feeling of tiredness)
- Asthenia (weakness)
- Confusional state
- Pain in extremity
- Back pain
- Dyspnoea (difficult or laboured respiration)
- Neuropathy peripheral (surface nerve damage)
- Pain
- Anaemia (lack of blood)
- Fall
50-59:
- Nasopharyngitis (inflammation of the nasopharynx)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
- Pyrexia (fever)
- Abdominal distension
- Abnormal dreams
- Arthralgia (joint pain)
- Asthenia (weakness)
- Blood calcium decreased
- Blood calcium increased
60+:
- Contusion (a type of hematoma of tissue in which capillaries)
- Arthralgia (joint pain)
- Fall
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gout (uric acid crystals building up in the body)
- Hepatitis (inflammation of the liver)
- Humerus fracture (injury to the upper arm bone)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Joint dislocation (a joint position is changed from normal position)
- Limb injury
What are the existing conditions these people have? *
- Mood Swings (an extreme or rapid change in mood): 8 people, 15.09%
- Pain: 7 people, 13.21%
- Stress And Anxiety: 3 people, 5.66%
- Psychotic Disorder: 3 people, 5.66%
- Immunodeficiency Common Variable: 3 people, 5.66%
- Bipolar Disorder (mood disorder): 3 people, 5.66%
- Asthma: 3 people, 5.66%
* Approximation only. Some reports may have incomplete information.
Do you take Augmentin and Wellbutrin sr?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Augmentin (42,620 reports)
- Wellbutrin sr (13,112 reports)
Browse all drug interactions of Augmentin and Wellbutrin sr:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Augmentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Wellbutrin sr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Wellbutrin sr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and bupropion hydrochloride (the active ingredients of Augmentin and Wellbutrin sr, respectively), and Augmentin and Wellbutrin sr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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