Pemetrexed and Ventricular extrasystoles - a phase IV clinical study of FDA data

Summary:

Ventricular extrasystoles is reported as a side effect among people who take Pemetrexed (pemetrexed), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Cisplatin, and have Lung adenocarcinoma.

The phase IV clinical study analyzes which people have Ventricular extrasystoles when taking Pemetrexed. It is created by eHealthMe based on reports of 17,478 people who have side effects when taking Pemetrexed from the FDA, and is updated regularly.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.

What is Ventricular extrasystoles?

Ventricular extrasystoles (premature cardiac contraction) is found to be associated with 1,246 drugs and 1,239 conditions by eHealthMe. Check the latest studies of Ventricular extrasystoles.

On Jul, 12, 2026

17,478 people reported to have side effects when taking Pemetrexed.
Among them, 13 people (0.07%) have Ventricular extrasystoles.

Could Pemetrexed cause Ventricular extrasystoles?

Among these 13 people:

How long have people been on Pemetrexed when they have Ventricular extrasystoles? *

What is the gender of people who have Ventricular extrasystoles when taking Pemetrexed? *

female: 38.46 %
male: 61.54 %

What is the age of people who have Ventricular extrasystoles when taking Pemetrexed? *

What are other drugs people take besides Pemetrexed? *

What are other side effects people have besides Ventricular extrasystoles? *

Nausea (feeling of having an urge to vomit): 10 people, 76.92%
Nausea And Vomiting: 9 people, 69.23%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 5 people, 38.46%
Roseolovirus Test Positive: 4 people, 30.77%
Malignant Neoplasm Progression (cancer tumour came back): 4 people, 30.77%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 4 people, 30.77%
Myocarditis (inflammation of heart muscle myocardium): 4 people, 30.77%
Cardiac Failure Acute: 4 people, 30.77%
Cardiogenic Shock (inadequate circulation of blood): 4 people, 30.77%
Parvovirus B19 Test Positive: 4 people, 30.77%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 4 people, 30.77%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 4 people, 30.77%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 2 people, 15.38%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 15.38%
Myocarditis (inflammation of heart muscle myocardium): 1 person, 7.69%
Lung Carcinoma Cell Type Unspecified Stage 0 (the lung cancer has not spread beyond the inner lining of the lung): 1 person, 7.69%
Lung Adenocarcinoma Stage Iii (the cancer has spread to nearby tissue or too far away lymph nodes): 1 person, 7.69%
Infection: 1 person, 7.69%
Diabetes: 1 person, 7.69%
Candidiasis (candidiasis or thrush is a fungal infection): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Pemetrexed and have Ventricular extrasystoles?

- Check whether Ventricular extrasystoles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pemetrexed:

Pemetrexed (17,491 reports)

Browse all side effects of Pemetrexed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular extrasystoles:

Ventricular extrasystoles (1,246 drugs)

Browse all the conditions that are associated with Ventricular extrasystoles:

Ventricular extrasystoles (1,239 conditions)

Related publications that referenced our studies

Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on pemetrexed (the active ingredients of Pemetrexed) and Pemetrexed (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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