Brintellix and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Acetaminophen (acetaminophen). Common drug interactions include coma among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Acetaminophen. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Aug, 11, 2026

33 people who take Brintellix and Acetaminophen together, and have interactions are studied.

Brintellix and Acetaminophen drug interactions.

What are the common drug interactions of Brintellix and Acetaminophen, by gender? *:

female:

Coma (state of unconsciousness lasting more than six hours)
Inappropriate antidiuretic hormone secretion
Asthenia (weakness)
Lethargy (tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Bradypnoea (an abnormally slow respiratory rate)
Hypersomnia (excessive daytime sleepiness (eds))
Poisoning deliberate
Confusional state
Drug ineffective

male:

Aggression
Abnormal behaviour
Malaise (a feeling of general discomfort or uneasiness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Negative thoughts
Overdose
Panic attack
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

What are the common drug interactions of Brintellix and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Poisoning deliberate
Bradypnoea (an abnormally slow respiratory rate)
Coma (state of unconsciousness lasting more than six hours)
Anxiety
Depressed level of consciousness
Drug ineffective
Poisoning
Sedation
Suicidal ideation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

30-39:

Overdose
Cerebral infarction (less blood supply to brain resulting tissue damage)
Coma (state of unconsciousness lasting more than six hours)
Hepatic enzyme increased
Loss of consciousness

40-49:

Dysgeusia (disorder of the sense of taste)
Photopsia (presence of perceived flashes of light)
Constipation
Hepatitis (inflammation of the liver)
Nausea (feeling of having an urge to vomit)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

50-59:

n/a

60+:

Inappropriate antidiuretic hormone secretion
Hypersomnia (excessive daytime sleepiness (eds))
Analgesic drug level increased
Coma (state of unconsciousness lasting more than six hours)
Psychomotor skills impaired
Sedation
Disease progression
Malaise (a feeling of general discomfort or uneasiness)
Asthenia (weakness)
Confusional state

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 18.18%
Insomnia (sleeplessness): 3 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.09%
Parkinson's Disease: 2 people, 6.06%
Neoplasm Malignant (cancer tumour): 2 people, 6.06%
Migraine (headache): 2 people, 6.06%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 6.06%
Joint Pain: 2 people, 6.06%
Gastritis (inflammation of stomach): 2 people, 6.06%
Essential Hypertension (primary hypertension): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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