Budesonide and Cotrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Budesonide (budesonide) and Cotrim (sulfamethoxazole; trimethoprim). Common drug interactions include pulmonary embolism among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Budesonide and Cotrim. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Budesonide?

Budesonide has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 42,933 Budesonide users. Check the latest studies of Budesonide.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

On Jul, 13, 2026

46 people who take Budesonide and Cotrim together, and have interactions are studied.

Budesonide and Cotrim drug interactions.

What are the common drug interactions of Budesonide and Cotrim, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Rash
Renal impairment (severely reduced kidney function)
Small intestinal haemorrhage (bleeding from small intestine)
Stem cell transplant
Thrombosis (formation of a blood clot inside a blood vessel)
Wound secretion
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood culture positive
Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)

male:

Hypotension (abnormally low blood pressure)
Anal fissure
Sepsis (a severe blood infection that can lead to organ failure and death)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Anal fistula
B-cell lymphoma (blood cancer affecting b cells)
Back pain
Heparin-induced thrombocytopenia
Proctitis (inflammation of the rectum and anus)
Psoas abscess (collection of pus in the iliopsoas muscle compartment)

What are the common drug interactions of Budesonide and Cotrim, by age (0-1 to 60+)? *:

0-1:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

2-9:

n/a

10-19:

Anal fissure
Perirectal abscess
Rectal abscess (pus in rectum)
Anal fistula
Heparin-induced thrombocytopenia
Proctitis (inflammation of the rectum and anus)
Abscess (pus)

20-29:

Hypokalaemia (low potassium)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Adenovirus test positive
Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Facial paresis (weakness in facial muscle movement)
Gastrointestinal erosion (gradual destruction of gastrointestinal tract because of the inflamed mucous membrane lining the stomach)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hemiparesis (weakness on one side of the body)

30-39:

Dyspnoea (difficult or laboured respiration)
Fall
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Limb injury
Pneumonia
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Renal failure acute (rapid kidney dysfunction)

40-49:

Bk virus infection
Cystitis haemorrhagic (blood in the urine and painful voiding)
Cytomegalovirus infection
Dehydration (dryness resulting from the removal of water)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypotension (abnormally low blood pressure)
Mucosal inflammation (infection of mucous membrane)
Sepsis (a severe blood infection that can lead to organ failure and death)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Ascites infection (bacterial infection due to accumulation of fluid in the abdominal cavity)

50-59:

Pyrexia (fever)
B-cell lymphoma (blood cancer affecting b cells)
Back pain
Psoas abscess (collection of pus in the iliopsoas muscle compartment)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

60+:

Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)
Asthenia (weakness)
Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)
Cardiac failure
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug administration error

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 19.57%
Febrile Neutropenia (fever with reduced white blood cells): 6 people, 13.04%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 13.04%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 13.04%
Allergies: 6 people, 13.04%
Bone Marrow Conditioning Regimen: 6 people, 13.04%
Cytomegalovirus Test Positive: 6 people, 13.04%
Depression: 6 people, 13.04%
Diarrhea: 6 people, 13.04%
Acute Graft Versus Host Disease In Intestine (acute complication in intestine following an allogeneic tissue/blood transplant): 6 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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