Bumex and Bidil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumex (bumetanide) and Bidil (hydralazine hydrochloride; isosorbide dinitrate). Common drug interactions include renal failure among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Bumex and Bidil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Bidil?

Bidil has active ingredients of hydralazine hydrochloride; isosorbide dinitrate. eHealthMe is studying from 520 Bidil users. Check the latest studies of Bidil.

On Jul, 09, 2026

18 people who take Bumex and Bidil together, and have interactions are studied.

What are the common drug interactions of Bumex and Bidil, by gender? *:

female:

Renal failure (kidney dysfunction)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Feeling hot
General physical health deterioration (weak health status)
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Oxygen saturation decreased

male:

Cardiac failure congestive
Chest pain
Insomnia (sleeplessness)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nausea (feeling of having an urge to vomit)
Abdominal discomfort

What are the common drug interactions of Bumex and Bidil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Abdominal pain upper
Chest pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Flatulence (flatus expelled through the anus)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Vision blurred
Vomiting

50-59:

Renal failure (kidney dysfunction)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Fatigue (feeling of tiredness)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nausea (feeling of having an urge to vomit)
Activities of daily living impaired
Anaemia (lack of blood)
Asthenia (weakness)
Cardiomyopathy (weakening of the heart muscle)

60+:

Cardiac failure congestive
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Dyspnoea (difficult or laboured respiration)
Feeling hot
General physical health deterioration (weak health status)
Hypertension (high blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Oxygen saturation decreased
Rales (an abnormal respiratory sound characterized by fine crackles)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 38.89%
Cardiac Failure: 6 people, 33.33%
High Blood Cholesterol: 5 people, 27.78%
Pain: 4 people, 22.22%
Diabetes: 3 people, 16.67%
Cardiac Failure Congestive: 3 people, 16.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
Infection: 3 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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