Celexa and Opana drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Opana (oxymorphone hydrochloride). Common drug interactions include hypersomnia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Opana. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

What is Opana?

Opana has active ingredients of oxymorphone hydrochloride. It is often used in pain. eHealthMe is studying from 40,340 Opana users. Check the latest studies of Opana.

On Jul, 19, 2026

62 people who take Celexa and Opana together, and have interactions are studied.

What are the common drug interactions of Celexa and Opana, by gender? *:

female:

Hypersomnia (excessive daytime sleepiness (eds))
Neuropathy peripheral (surface nerve damage)
Suicidal ideation
Therapeutic response decreased (less preventive response)
Drug abuse
Hypoaesthesia (reduced sense of touch or sensation)
Injection site pain
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Psoriasis (immune-mediated disease that affects the skin)
Aggression

male:

Drug ineffective
Gait disturbance
Alanine aminotransferase increased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arachnoid cyst
Chronic kidney disease
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Diarrhoea
Disability
Drug dependence

What are the common drug interactions of Celexa and Opana, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Accidental death
Alcohol poisoning
Drug screen positive
Drug toxicity
Epistaxis (bleed from the nose)
Multiple drug overdose
Unresponsive to stimuli

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Drug abuse
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Laryngitis (inflammation of the larynx)
Local swelling (swelling at the site of some application of substance or injury)
Lymphadenopathy (disease or enlargement of lymph nodes)
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

40-49:

Constipation
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hypersomnia (excessive daytime sleepiness (eds))
Therapeutic response decreased (less preventive response)
Vomiting
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac failure acute
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Hypertensive heart disease

50-59:

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Gait disturbance
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Tremor (trembling or shaking movements in one or more parts of your body)
Suicidal ideation
Diarrhoea
Chest pain
Abnormal faeces (abnormal stool)
Arthralgia (joint pain)
Asthenia (weakness)

60+:

Abdominal pain
Feeling of body temperature change
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Completed suicide (act of taking one's own life)
Death
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dysuria (painful or difficult urination)
Haemoglobin decreased
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Breakthrough Pain: 8 people, 12.90%
Stress And Anxiety: 7 people, 11.29%
Neuralgia (pain in one or more nerves): 7 people, 11.29%
Wheezing (a high-pitched whistling sound made while you breath): 5 people, 8.06%
Sleep Disorder: 5 people, 8.06%
Neuropathy Peripheral (surface nerve damage): 5 people, 8.06%
Nausea (feeling of having an urge to vomit): 5 people, 8.06%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 8.06%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 5 people, 8.06%
Back Pain: 5 people, 8.06%

* Approximation only. Some reports may have incomplete information.

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