Ciclosporin and Ambisome drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ciclosporin (cyclosporine) and Ambisome (amphotericin b). Common drug interactions include gastrointestinal disorder among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ciclosporin and Ambisome. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Ciclosporin?

Ciclosporin has active ingredients of cyclosporine. eHealthMe is studying from 3,571 Ciclosporin users. Check the latest studies of Ciclosporin.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.

On Jul, 19, 2026

11 people who take Ciclosporin and Ambisome together, and have interactions are studied.

Ciclosporin and Ambisome drug interactions.

What are the common drug interactions of Ciclosporin and Ambisome, by gender? *:

female:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infection
Mucocutaneous leishmaniasis (partial or total destruction of the mucous membranes of the nose, mouth and throat cavities)
Pathogen resistance
Visceral leishmaniasis (black fever)
Drug ineffective
Abdominal pain upper
Capillary leak syndrome (capillary leaks plasma)
Cardiac failure acute
Cardiac failure congestive

male:

Anaemia (lack of blood)
Decreased appetite
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Pallor
Pleural effusion (water on the lungs)
Rash
Reversible posterior leukoencephalopathy syndrome (a brain disease with generalized seizures and headache)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Inflammatory marker increased
Lung disorder (lung disease)

What are the common drug interactions of Ciclosporin and Ambisome, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Anaemia (lack of blood)
Decreased appetite
Inflammatory marker increased
Lung disorder (lung disease)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Capillary leak syndrome (capillary leaks plasma)
Respiratory distress (difficulty in breathing)

10-19:

Histiocytosis haematophagic
Human herpesvirus 6 infection
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

20-29:

Bacteraemia (presence of bacteria in the blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Fall
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Pleural effusion (water on the lungs)
Reversible posterior leukoencephalopathy syndrome (a brain disease with generalized seizures and headache)

30-39:

n/a

40-49:

Cardiac failure acute
Cardiac failure congestive
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypovolaemia (a decreased volume of circulating blood in the body)
Immunosuppressant drug level increased
Influenza like illness
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Psychotic disorder
Sleep disorder

50-59:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infection
Mucocutaneous leishmaniasis (partial or total destruction of the mucous membranes of the nose, mouth and throat cavities)
Pathogen resistance
Visceral leishmaniasis (black fever)
Pallor
Rash
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

60+:

n/a

What are the existing conditions these people have? *

Epstein-Barr Virus Infection: 3 people, 27.27%
Post Transplant Lymphoproliferative Disorder: 3 people, 27.27%
Lung Disorder (lung disease): 3 people, 27.27%
Immunodeficiency Disorders: 3 people, 27.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
Visceral Leishmaniasis (black fever): 1 person, 9.09%
Aspergillosis (an infection caused by a fungus called aspergillus): 1 person, 9.09%
Bone Marrow Conditioning Regimen: 1 person, 9.09%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 1 person, 9.09%
Cryoglobulinaemia (blood contains large amounts of cryoglobulins - proteins): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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