Cimetidine and Zetia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cimetidine (cimetidine) and Zetia (ezetimibe). Common drug interactions include nausea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Zetia. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

On Jul, 16, 2026

77 people who take Cimetidine and Zetia together, and have interactions are studied.

What are the common drug interactions of Cimetidine and Zetia, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Vomiting
Abdominal distension
Abdominal pain
Ankle fracture
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Constipation
Depression
Drug ineffective

male:

Chronic kidney disease
Dizziness
Hypersensitivity
Injection site haematoma (localized swelling filled with blood at injection site)
Myalgia (muscle pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Vomiting
Abdominal discomfort
Abdominal pain upper
Arteriosclerosis (thickening and hardening of arteries)

What are the common drug interactions of Cimetidine and Zetia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Chronic kidney disease
Depression
Renal failure (kidney dysfunction)

30-39:

n/a

40-49:

Chronic kidney disease
Renal injury (kidney injury)
Renal failure (kidney dysfunction)
Acute respiratory failure
Arthralgia (joint pain)
Bone pain
Breast pain
Cardiac arrest
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Death

50-59:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Drug ineffective
Ear pain
Facial bones fracture (bone fracture of face)
Fall
Gastrointestinal stromal tumour (a cancer that arises from transformed cells of mesenchymal origin in gastrointestinal tract)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypovolaemia (a decreased volume of circulating blood in the body)
International normalised ratio increased
Loss of consciousness
Renal failure acute (rapid kidney dysfunction)
Urinary tract infection

What are the existing conditions these people have? *

High Blood Pressure: 28 people, 36.36%
Pain: 21 people, 27.27%
Depression: 20 people, 25.97%
Diabetes: 15 people, 19.48%
Infection: 13 people, 16.88%
Stress And Anxiety: 11 people, 14.29%
Gastric Ulcer (stomach ulcer): 10 people, 12.99%
Migraine (headache): 10 people, 12.99%
Muscle Spasms (muscle contraction): 9 people, 11.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 11.69%

* Approximation only. Some reports may have incomplete information.

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