Cinnamon and Naproxen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cinnamon (cassia cinnamon) and Naproxen (naproxen). Common drug interactions include musculoskeletal stiffness among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Cinnamon and Naproxen. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Cinnamon?

Cinnamon has active ingredients of cassia cinnamon. It is often used in diabetes. eHealthMe is studying from 4,110 Cinnamon users. Check the latest studies of Cinnamon.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

On Jul, 09, 2026

43 people who take Cinnamon and Naproxen together, and have interactions are studied.

Cinnamon and Naproxen drug interactions.

What are the common drug interactions of Cinnamon and Naproxen, by gender? *:

female:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Neck pain
Osteomyelitis (infection of bone)
Pain in extremity
Paranasal sinus discomfort
Photophobia (extreme sensitivity to light)
Pleuritic pain
Pruritus generalised (generalized itching)

male:

Abdominal discomfort
Blood cholesterol increased
Dizziness
Protein urine
Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
Gangrene (body tissue dies)
Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Arthralgia (joint pain)
Blood glucose increased

What are the common drug interactions of Cinnamon and Naproxen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood pressure increased
Dizziness
Fatigue (feeling of tiredness)
Fear
Lethargy (tiredness)
Loss of consciousness
Nightmare (unpleasant dream)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

Asthenia (weakness)
Limb discomfort (discomfort in leg)
Pain in extremity

50-59:

Sinus headache (headache caused by sinus infections)
Tendonitis (a condition that causes pain and swelling of tendons)
Toothache (tooth pain)
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Vulvovaginal discomfort
Vulvovaginal dryness
Dyspnoea (difficult or laboured respiration)
Burning sensation
Erythema (redness of the skin)

60+:

Drug ineffective
Abdominal discomfort
Confusional state
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Joint swelling
Mobility decreased (ability to move is reduced)
Neck pain
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 18.60%
Type 2 Diabetes: 7 people, 16.28%
High Blood Cholesterol: 7 people, 16.28%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 13.95%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 11.63%
Tooth Abscess (pus formation in tooth): 3 people, 6.98%
Quit Smoking: 3 people, 6.98%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.98%
Inflammation: 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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