Citrus and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Citrus (grapefruit) and Flonase (fluticasone propionate). Common drug interactions include hypokalaemia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Citrus and Flonase. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Citrus?

Citrus has active ingredients of grapefruit. eHealthMe is studying from 201 Citrus users. Check the latest studies of Citrus.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

On Jul, 30, 2026

13 people who take Citrus and Flonase together, and have interactions are studied.

What are the common drug interactions of Citrus and Flonase, by gender? *:

female:

Hypokalaemia (low potassium)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Genitourinary tract infection (infection of genital tract and urinary tract)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Abdominal pain upper
Anxiety
Decreased appetite
Depression
Diarrhoea

male:

Anaemia (lack of blood)
Hepatic cyst
Anal pruritus (anal itching)
Cholangitis (infection of the bile duct)
Cough
Genital discomfort
Glucose urine present
Liver disorder (liver diseases)
Mobility decreased (ability to move is reduced)
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)

What are the common drug interactions of Citrus and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Acne (skin problems that cause pimples)
Arthralgia (joint pain)
Blindness
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cholangitis (infection of the bile duct)
Eye swelling
Muscular weakness (muscle weakness)
Psoriasis (immune-mediated disease that affects the skin)
Rash
Scar

60+:

Hypokalaemia (low potassium)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Decreased appetite
Depression
Diarrhoea
Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatomegaly (abnormal enlargement of the liver)
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 38.46%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 30.77%
Hypersensitivity: 3 people, 23.08%
Stress And Anxiety: 2 people, 15.38%
Sleep Disorder: 2 people, 15.38%
Cough: 2 people, 15.38%
Oral Herpes (viral infection of mouth): 2 people, 15.38%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%
Cystic Fibrosis (disease of the secretary glands): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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