Cladribine and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cladribine (cladribine) and Profen (ibuprofen). Common drug interactions include erythema among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Cladribine and Profen. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Cladribine?

Cladribine has active ingredients of cladribine. eHealthMe is studying from 2,540 Cladribine users. Check the latest studies of Cladribine.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 16, 2026

35 people who take Cladribine and Profen together, and have interactions are studied.

Cladribine and Profen drug interactions.

What are the common drug interactions of Cladribine and Profen, by gender? *:

female:

Erythema (redness of the skin)
Red blood cell sedimentation rate increased
Depressed mood
Dyspnoea (difficult or laboured respiration)
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Angular cheilitis (inflammation of one, or more commonly both, of the corners of the mouth)
Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Blood oestrogen increased

male:

Constipation
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Teething (process by which an infant's first teeth grows)
Drug ineffective
Myalgia (muscle pain)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Hypersensitivity
Drug dependence
Drug intolerance (drug sensitivity)
Gingival pain (gum pain)

What are the common drug interactions of Cladribine and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Gingival pain (gum pain)
Toothache (tooth pain)
Myalgia (muscle pain)
Erythema (redness of the skin)
Therapeutic response decreased (less preventive response)
Anaphylactic reaction (serious allergic reaction)
Teething (process by which an infant's first teeth grows)
Red blood cell sedimentation rate increased
Drug ineffective
Acne (skin problems that cause pimples)

50-59:

Lymphopenia (an abnormally low level of lymphocytes in the blood)
Kidney infection
Lymphocyte count decreased
Radius fracture

60+:

n/a

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 16 people, 45.71%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 14 people, 40.00%
Joint Pain: 14 people, 40.00%
Exostosis (formation of new bone on the surface of a bone): 9 people, 25.71%
Bone Pain: 9 people, 25.71%
Acne (skin problems that cause pimples): 9 people, 25.71%
Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 5 people, 14.29%
Oesophageal Pain: 3 people, 8.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.57%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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