Clindesse and Ibuprofen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clindesse (clindamycin phosphate) and Ibuprofen (ibuprofen). Common drug interactions include escherichia infection among females and abdominal adhesions among males.
The phase IV clinical study analyzes what interactions people have when they take Clindesse and Ibuprofen. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Clindesse?
Clindesse has active ingredients of clindamycin phosphate. eHealthMe is studying from 202 Clindesse users. Check the latest studies of Clindesse.
What is Ibuprofen?
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.
37 people who take Clindesse and Ibuprofen together, and have interactions are studied.

What are the common drug interactions of Clindesse and Ibuprofen, by gender? *:
female:
- Escherichia infection (bacterial infection by escherichia coli)
- Eye injury
- Eye irritation
- Multiple injuries
- Presyncope
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Urinary retention (the inability to completely or partially empty the bladder)
- Uveitis (inflammation of the uvea)
- Blood glucose increased
- Chest discomfort
male:
- Abdominal adhesions (inflammation of abdomen)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Attention deficit/hyperactivity disorder
- Autonomic failure syndrome (a degenerative disease of the autonomic nervous system)
- Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
- Blood glucose fluctuation
- Cardiolipin antibody positive
- Cerebellar ataxia (loss of coordination)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
What are the common drug interactions of Clindesse and Ibuprofen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abdominal discomfort
- Dehydration (dryness resulting from the removal of water)
- Nausea (feeling of having an urge to vomit)
- Proteinuria (presence of protein in the urine)
- Renal failure (kidney dysfunction)
- Renal failure acute (rapid kidney dysfunction)
- Vomiting
20-29:
- Gallbladder disorder
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Cholecystitis (infection of gallbladder)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pulmonary embolism (blockage of the main artery of the lung)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
30-39:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Death
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dyspepsia (indigestion)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Pulmonary artery thrombosis (blockage of the main artery of the lung)
40-49:
- Ankle fracture
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Fall
- Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
- Thrombosis (formation of a blood clot inside a blood vessel)
- Bradycardia (abnormally slow heart action)
- Cardiac disorder
- Depression
- Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
50-59:
- Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
- Viral infection
- White blood cell count increased
- Abdominal pain
- Blindness unilateral
- Blood glucose increased
- Cataract (clouding of the lens inside the eye)
- Corneal abrasion (loss of the surface of cornea)
- Cough
- Diarrhoea
60+:
- Anxiety
- Asthenia (weakness)
- Abdominal pain
- Blindness unilateral
- Blood glucose decreased
- Cardiac failure congestive
- Cough
- Escherichia infection (bacterial infection by escherichia coli)
- Eye irritation
- Hyperhidrosis (abnormally increased sweating)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 32.43%
- High Blood Pressure: 9 people, 24.32%
- Diabetes: 8 people, 21.62%
- Fungal Infection: 7 people, 18.92%
- Psoriasis (immune-mediated disease that affects the skin): 7 people, 18.92%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 18.92%
- Depression: 6 people, 16.22%
- High Blood Cholesterol: 5 people, 13.51%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 13.51%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 13.51%
* Approximation only. Some reports may have incomplete information.
Do you take Clindesse and Ibuprofen?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Clindesse and Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clindesse:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clindesse and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibuprofen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on clindamycin phosphate and ibuprofen (the active ingredients of Clindesse and Ibuprofen, respectively), and Clindesse and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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