Clonazepam and Duragesic-50 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clonazepam (clonazepam) and Duragesic-50 (fentanyl). Common drug interactions include pain in extremity among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Clonazepam and Duragesic-50. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,271 Clonazepam users. Check the latest studies of Clonazepam.

What is Duragesic-50?

Duragesic-50 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 733 Duragesic-50 users. Check the latest studies of Duragesic-50.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

11 people who take Clonazepam and Duragesic-50 together, and have interactions are studied.

Clonazepam and Duragesic-50 drug interactions.

What are the common drug interactions of Clonazepam and Duragesic-50, by gender? *:

female:

Pain in extremity
Spinal column stenosis (narrowing of spinal column)
Therapeutic response decreased (less preventive response)
Depression
Breast cancer
Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chest pain
Dry skin
Emotional distress

male:

Abdominal pain
Adrenal neoplasm (abnormal growth of adrenal gland)
Bone pain
Breast tenderness
Calculus bladder (bladder stone)
Chills (felling of cold)
Colitis (inflammation of colon)
Concomitant disease progression (progress in accompanying disease)
Constipation
Dental discomfort

What are the common drug interactions of Clonazepam and Duragesic-50, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Biliary cyst
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Blood testosterone decreased
Blood urine present
Bone density decreased
Bone disorder
Bone pain
Breast tenderness

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Activities of daily living impaired
Chest pain
Dry skin
Emotional distress
Hypoaesthesia (reduced sense of touch or sensation)
Joint contracture (a permanent shortening of a muscle or joint)
Joint stiffness
Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)

60+:

Breast cancer
Depression
Pain in extremity
Spinal column stenosis (narrowing of spinal column)
Therapeutic response decreased (less preventive response)
Non-hodgkin's lymphoma stage i (malignant (cancer) cells form in the lymph system- stage i)
B-cell lymphoma (blood cancer affecting b cells)
Body height decreased
Decreased appetite
Disturbance in attention

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 36.36%
Anaemia (lack of blood): 3 people, 27.27%
Prostate Cancer: 3 people, 27.27%
Nuclear Magnetic Resonance Imaging Brain: 3 people, 27.27%
Diabetes: 3 people, 27.27%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 18.18%
Bone Pain: 2 people, 18.18%
Breakthrough Pain: 2 people, 18.18%
Cardiac Disorder: 2 people, 18.18%
Depression: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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