Bendamustine and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bendamustine (bendamustine) and Ibuprofen (ibuprofen). Common drug interactions include folliculitis among females and hydronephrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Bendamustine and Ibuprofen. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Bendamustine?

Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

52 people who take Bendamustine and Ibuprofen together, and have interactions are studied.

Bendamustine and Ibuprofen drug interactions.

What are the common drug interactions of Bendamustine and Ibuprofen, by gender? *:

female:

Folliculitis (infection of hair root)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
General physical health deterioration (weak health status)
Glossodynia (a burning or painful sensation in the tongue)
Hand deformity
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hip arthroplasty
Hypersensitivity
Hypertension (high blood pressure)

male:

Hydronephrosis (water inside the kidney)
Myelosuppression (a decrease in the production of blood cells)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Cystitis noninfective (non-infectious inflammation of the wall of the bladder)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Death
Eye haemorrhage (bleeding in the eye)
Febrile neutropenia (fever with reduced white blood cells)
Impaired work ability
Infectious pleural effusion (infectious fluid in the lung)

What are the common drug interactions of Bendamustine and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Febrile neutropenia (fever with reduced white blood cells)
Myelosuppression (a decrease in the production of blood cells)
Night sweats (sweating in night)
Pyrexia (fever)
Cough
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

50-59:

Hip arthroplasty
Hypersensitivity
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Ill-defined disorder
Impaired healing
Infection
Inflammation
Infusion related reaction
Injury

60+:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pneumonia
Blood alkaline phosphatase increased
Blood calcium decreased
Blood glucose increased
Blood lactate dehydrogenase increased
Blood phosphorus decreased
Blood triglycerides increased
Blood urea decreased
Blood uric acid decreased

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 30 people, 57.69%
Fever: 17 people, 32.69%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 9 people, 17.31%
Back Pain: 9 people, 17.31%
Constipation: 9 people, 17.31%
Burkitt Lymphoma (cancer of the lymphatic system): 8 people, 15.38%
Productive Cough: 7 people, 13.46%
Pain In Extremity: 7 people, 13.46%
Osteoporosis (bones weak and more likely to break): 7 people, 13.46%
Nausea (feeling of having an urge to vomit): 7 people, 13.46%

* Approximation only. Some reports may have incomplete information.

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