Clopidogrel and Zanaflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopidogrel (clopidogrel) and Zanaflex (tizanidine hydrochloride). Common drug interactions include renal injury among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Clopidogrel and Zanaflex. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

On Jun, 18, 2026

61 people who take Clopidogrel and Zanaflex together, and have interactions are studied.

Clopidogrel and Zanaflex drug interactions.

What are the common drug interactions of Clopidogrel and Zanaflex, by gender? *:

female:

Renal injury (kidney injury)
Acute myocardial infarction (acute heart attack)
Acute respiratory failure
Anaemia (lack of blood)
Arthralgia (joint pain)
Bone pain
Cardiac failure congestive
Confusional state
Constipation
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Death
Diarrhoea
Dyslipidaemia (abnormal amount of lipids)
Fall
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Clopidogrel and Zanaflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Constipation
Nephrogenic anaemia (anaemia due to kidney disease)
Renal cyst (kidney cyst)
Acidosis (build-up of carbon dioxide in the blood)
Gastric cancer (stomach cancer)
Hypervolaemia (abnormally increased volume of blood)
Acute myocardial infarction (acute heart attack)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Balance disorder
Blood pressure increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 34.43%
High Blood Pressure: 14 people, 22.95%
Pain: 11 people, 18.03%
High Blood Cholesterol: 11 people, 18.03%
Cardiac Disorder: 7 people, 11.48%
Renal Disorder (kidney disease): 6 people, 9.84%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 9.84%
Infection: 6 people, 9.84%
Gastric Ulcer (stomach ulcer): 6 people, 9.84%
Stress And Anxiety: 5 people, 8.20%

* Approximation only. Some reports may have incomplete information.

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