Clopra and Mirabegron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Mirabegron (mirabegron). Common drug interactions include nausea among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Mirabegron. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Mirabegron?

Mirabegron has active ingredients of mirabegron. It is often used in urge incontinence. eHealthMe is studying from 5,414 Mirabegron users. Check the latest studies of Mirabegron.



On Jul, 18, 2026

86 people who take Clopra and Mirabegron together, and have interactions are studied.

Clopra and Mirabegron drug interactions.

What are the common drug interactions of Clopra and Mirabegron, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Poor quality sleep
  3. Septic shock (shock due to blood infection)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Tooth fracture
  6. Urinary retention (the inability to completely or partially empty the bladder)
  7. Weight decreased
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Alopecia (absence of hair from areas of the body)

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Haematuria (presence of blood in urine)
  3. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Infusion related reaction
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Benign prostatic hyperplasia (benign enlargement of the prostate)
  10. Neoplasm (tumour)

What are the common drug interactions of Clopra and Mirabegron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Urinary retention (the inability to completely or partially empty the bladder)
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Pyrexia (fever)
  4. Renal infarct (kidney damage due to lack of blood supply)
  5. Urinary tract infection
  6. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  7. Cystitis haemorrhagic (blood in the urine and painful voiding)
  8. Gastritis (inflammation of stomach)
  9. Haematuria (presence of blood in urine)
  10. Hypokalaemia (low potassium)

40-49:

  1. Osteomyelitis (infection of bone)
  2. Headache (pain in head)
  3. Abdominal pain upper
  4. Alopecia (absence of hair from areas of the body)
  5. Cardiac failure acute
  6. Chest pain
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Cold sweat
  9. Diarrhoea
  10. Dyspnoea (difficult or laboured respiration)

50-59:

  1. Frequent bowel movements
  2. Haemorrhage (bleeding)
  3. Hypercholesterolaemia (high levels of cholesterol in the blood)
  4. Hypersensitivity
  5. Implant site extravasation
  6. Infusion site rash
  7. Lymphoma (cancer that begins in immune system cells)
  8. Muscle spasms (muscle contraction)
  9. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)

60+:

  1. Cardiac failure
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Arthralgia (joint pain)
  4. Back injury
  5. Back pain
  6. Blood glucose increased
  7. Blood pressure systolic increased
  8. Body temperature increased
  9. Diarrhoea
  10. Hepatic lesion

What are the existing conditions these people have? *

  1. Constipation: 30 people, 34.88%
  2. Nausea (feeling of having an urge to vomit): 26 people, 30.23%
  3. Pain: 19 people, 22.09%
  4. High Blood Pressure: 19 people, 22.09%
  5. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 15 people, 17.44%
  6. Insomnia (sleeplessness): 14 people, 16.28%
  7. Enlarged Prostate: 12 people, 13.95%
  8. Thrombocytopenia (decrease of platelets in blood): 11 people, 12.79%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 12.79%
  10. Rashes (redness): 10 people, 11.63%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and Mirabegron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clopra and Mirabegron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mirabegron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clopra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirabegron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride and mirabegron (the active ingredients of Clopra and Mirabegron, respectively), and Clopra and Mirabegron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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