Clopra and Stavudine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Stavudine (stavudine). Common drug interactions include arthralgia among females and lactic acidosis among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Stavudine. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Stavudine?

Stavudine has active ingredients of stavudine. eHealthMe is studying from 10,319 Stavudine users. Check the latest studies of Stavudine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

50 people who take Clopra and Stavudine together, and have interactions are studied.

What are the common drug interactions of Clopra and Stavudine, by gender? *:

female:

Arthralgia (joint pain)
Blood alkaline phosphatase increased
Blood lactic acid increased
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Gamma-glutamyltransferase increased

male:

Lactic acidosis (low ph in body tissues)
Nausea (feeling of having an urge to vomit)
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Pyrexia (fever)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood bilirubin increased
Blood creatinine increased
Blood triglycerides increased
Chest pain
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Clopra and Stavudine, by age (0-1 to 60+)? *:

0-1:

Blood lactic acid increased
Hypertriglyceridaemia (excess of triglycerides in the blood)
Hypospadias (an abnormal condition in males in which the urethra opens on the under surface of the penis)
Neutropenia (an abnormally low number of neutrophils)

2-9:

Urinary retention (the inability to completely or partially empty the bladder)

10-19:

Family stress
Renal tubular disorder (disease of kidney tubules)
Tardive dyskinesia (a disorder that involves involuntary movements)

20-29:

n/a

30-39:

Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Infection
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Pancreatitis acute (sudden inflammation of pancreas)
Periorbital oedema (swelling around the eyes)
Platelet count decreased
Prostatic disorder
Prostatitis (inflammation of the prostate gland)

40-49:

Hepatotoxicity (chemical-driven liver damage)
Hepatic failure (liver failure)
Lactic acidosis (low ph in body tissues)
Pyrexia (fever)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neutropenia (an abnormally low number of neutrophils)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

50-59:

Pancreatitis acute (sudden inflammation of pancreas)

60+:

Abdominal pain
Adult respiratory distress syndrome (type of lung (pulmonary) failure)
Hypotension (abnormally low blood pressure)
Laboratory test abnormal
Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)
Pleural effusion (water on the lungs)
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

Hiv Infection: 13 people, 26.00%
Mycobacterium Avium Complex Infection: 4 people, 8.00%
Penicilliosis (infection caused by fungus penicillium marneffei): 3 people, 6.00%
Neuropathy Peripheral (surface nerve damage): 3 people, 6.00%
Nausea (feeling of having an urge to vomit): 3 people, 6.00%
Herpes Zoster: 3 people, 6.00%
Heart Attack: 3 people, 6.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.00%
Diabetes: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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