Cometriq and Escitalopram drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cometriq (cabozantinib s-malate) and Escitalopram (escitalopram oxalate). Common drug interactions include cystitis among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Cometriq and Escitalopram. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Cometriq?
Cometriq has active ingredients of cabozantinib s-malate. eHealthMe is studying from 2,712 Cometriq users. Check the latest studies of Cometriq.
What is Escitalopram?
Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,080 Escitalopram users. Check the latest studies of Escitalopram.
14 people who take Cometriq and Escitalopram together, and have interactions are studied.

What are the common drug interactions of Cometriq and Escitalopram, by gender? *:
female:
- Cystitis (inflammation of the wall of the bladder)
- Death
- Dehydration (dryness resulting from the removal of water)
- Depressed mood
- Diarrhoea
- Acne (skin problems that cause pimples)
- Adverse drug reaction
- Fatigue (feeling of tiredness)
- Gingival bleeding (bleeding gums)
- Scab (a hard coating on the skin formed during the wound healing)
male:
- Diarrhoea
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Oropharyngeal pain
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Adverse drug reaction
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Glossodynia (a burning or painful sensation in the tongue)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Anorectal discomfort
- Dysgeusia (disorder of the sense of taste)
What are the common drug interactions of Cometriq and Escitalopram, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Glossodynia (a burning or painful sensation in the tongue)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Platelet count decreased
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Death
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
60+:
- Diarrhoea
- Fatigue (feeling of tiredness)
- Glossodynia (a burning or painful sensation in the tongue)
- Oropharyngeal pain
- Death
What are the existing conditions these people have? *
- Thyroid Cancer: 8 people, 57.14%
- Metastases To Lung (cancer spreads to lung): 3 people, 21.43%
- Breast Cancer Female: 3 people, 21.43%
- Metastases To Central Nervous System (cancer spreads to central nervous system): 2 people, 14.29%
- Gastric Cancer (stomach cancer): 2 people, 14.29%
- Renal Cell Carcinoma (a kidney cancer): 1 person, 7.14%
- Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 7.14%
- Connective Tissue Neoplasm (tumour of connective tissue): 1 person, 7.14%
- Breast Cancer: 1 person, 7.14%
- Brain Neoplasm Malignant (brain cancer tumour): 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Cometriq and Escitalopram?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cometriq (2,712 reports)
- Escitalopram (78,080 reports)
Browse all drug interactions of Cometriq and Escitalopram:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cometriq:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Escitalopram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cometriq and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Escitalopram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cabozantinib s-malate and escitalopram oxalate (the active ingredients of Cometriq and Escitalopram, respectively), and Cometriq and Escitalopram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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