Cortril and Januvia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cortril (hydrocortisone) and Januvia (sitagliptin phosphate). Common drug interactions include cushing's syndrome among females and platelet count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Cortril and Januvia. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Cortril?

Cortril has active ingredients of hydrocortisone. eHealthMe is studying from 1,715 Cortril users. Check the latest studies of Cortril.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

On Jul, 11, 2026

24 people who take Cortril and Januvia together, and have interactions are studied.

What are the common drug interactions of Cortril and Januvia, by gender? *:

female:

Cushing's syndrome (obesity, a rounded face, increased fat)
Hepatic steatosis (fatty liver disease)
Hypertension (high blood pressure)
Neuralgia (pain in one or more nerves)
Sudden death
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Epstein-barr virus infection
Acute myocardial infarction (acute heart attack)
Altered state of consciousness (altered state of mind)
Asterixis (flapping tremor, or liver flap)

male:

Platelet count decreased
Back pain
Anaemia (lack of blood)
Platelet count increased
White blood cell count increased
Diarrhoea
Infection
Vomiting
Cholangitis sclerosing (infection and obstruction of bile duct)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

What are the common drug interactions of Cortril and Januvia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cushing's syndrome (obesity, a rounded face, increased fat)
Hepatic steatosis (fatty liver disease)
Hypertension (high blood pressure)
Neuralgia (pain in one or more nerves)
Sudden death

50-59:

n/a

60+:

Platelet count decreased
Diarrhoea
Pneumonia
Altered state of consciousness (altered state of mind)
Asterixis (flapping tremor, or liver flap)
Blood glucose increased
Blood lactate dehydrogenase increased
Blood thyroid stimulating hormone decreased
C-reactive protein increased
Decreased appetite

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 33.33%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 7 people, 29.17%
Osteoporosis (bones weak and more likely to break): 7 people, 29.17%
Anaemia (lack of blood): 5 people, 20.83%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 20.83%
Neuralgia (pain in one or more nerves): 5 people, 20.83%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 20.83%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 20.83%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 20.83%
Type 2 Diabetes: 5 people, 20.83%

* Approximation only. Some reports may have incomplete information.

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