Cozaar and Mercaptopurine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Mercaptopurine (mercaptopurine). Common drug interactions include blood glucose increased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Mercaptopurine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.



On Jul, 12, 2026

11 people who take Cozaar and Mercaptopurine together, and have interactions are studied.

Cozaar and Mercaptopurine drug interactions.

What are the common drug interactions of Cozaar and Mercaptopurine, by gender? *:

female:

  1. Blood glucose increased
  2. Cataract (clouding of the lens inside the eye)
  3. Chest pain
  4. Drug ineffective
  5. Herpes zoster
  6. Inflammation
  7. Neck pain
  8. Oedema peripheral (superficial swelling)
  9. Protein urine present
  10. Pyrexia (fever)

male:

  1. Asthenia (weakness)
  2. Dieulafoy's vascular malformation (dieulafoy's vascular malformation may cause severe, potentially life-threatening gastro-intestinal bleeding)
  3. Gastric ulcer (stomach ulcer)
  4. International normalised ratio increased
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Cozaar and Mercaptopurine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Oropharyngeal pain
  2. Oropharyngeal plaque (hard deposit on oropharynx)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Osteolysis (dissolution of bone)
  5. Osteomyelitis (infection of bone)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Pain
  8. Pain in extremity
  9. Painful respiration
  10. Paranasal sinus discomfort

20-29:

n/a

30-39:

n/a

40-49:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Chest pain
  3. Erythema (redness of the skin)
  4. Female genital tract fistula (passage in genital tract of female)
  5. Histoplasmosis (infection caused by breathing in spores of a fungus)
  6. Hypocholesterolaemia (presence of abnormally small amounts of cholesterol in the circulating blood)
  7. Injury
  8. Lymph node calcification (calcium deposit in lymph node)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Neck pain

50-59:

  1. Cataract (clouding of the lens inside the eye)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Infection
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pancreatitis (inflammation of pancreas)
  6. Polymyalgia rheumatica (pain in many muscles)
  7. Weight increased

60+:

  1. Asthenia (weakness)
  2. Alopecia (absence of hair from areas of the body)
  3. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  4. Rib fracture
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Spinal fracture (fracture in one of vertebrae)
  7. Weight increased
  8. Back pain
  9. Crying
  10. Cushing's syndrome (obesity, a rounded face, increased fat)

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 36.36%
  2. Pain: 2 people, 18.18%
  3. Diabetes: 2 people, 18.18%
  4. Type 2 Diabetes: 1 person, 9.09%
  5. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 9.09%
  6. High Blood Cholesterol: 1 person, 9.09%
  7. Dyspnea (difficult or laboured breathing): 1 person, 9.09%
  8. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 9.09%
  9. Constipation: 1 person, 9.09%
  10. Breast Cancer: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Cozaar and Mercaptopurine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cozaar and Mercaptopurine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mercaptopurine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cozaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mercaptopurine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and mercaptopurine (the active ingredients of Cozaar and Mercaptopurine, respectively), and Cozaar and Mercaptopurine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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