Creon and Imitrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Creon (pancrelipase (amylase;lipase;protease)) and Imitrex (sumatriptan succinate). Common drug interactions include malaise among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Creon and Imitrex. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

On Aug, 08, 2026

14 people who take Creon and Imitrex together, and have interactions are studied.

What are the common drug interactions of Creon and Imitrex, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Abdominal pain
Asthenia (weakness)
Blood amylase increased
Hypophagia (reduced food intake)
Lower respiratory tract infection
Memory impairment
Vomiting projectile

male:

Chest pain
Headache (pain in head)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Night sweats (sweating in night)
Productive cough
Pruritus (severe itching of the skin)
Pseudomonas test positive
Pyrexia (fever)
Secretion discharge
Sputum discoloured

What are the common drug interactions of Creon and Imitrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain upper
Dehydration (dryness resulting from the removal of water)
Heart rate increased
Nausea (feeling of having an urge to vomit)
Vomiting

20-29:

Headache (pain in head)
Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

Asthenia (weakness)
Chest discomfort
Chest pain
Cough
Decreased appetite
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

40-49:

Flushing (the warm, red condition of human skin)
Gastric disorder (disease of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hemiparesis (weakness on one side of the body)
Hot flush (sudden feelings of heat)
Influenza
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Non-cardiac chest pain

50-59:

Abdominal discomfort
Abdominal pain lower
Back pain
Chest pain
Drug effect decreased
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Rectal haemorrhage (bleeding from anus)

60+:

n/a

What are the existing conditions these people have? *

Pain: 6 people, 42.86%
Cystic Fibrosis (disease of the secretary glands): 4 people, 28.57%
Indigestion: 3 people, 21.43%
Osteoporosis (bones weak and more likely to break): 3 people, 21.43%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 21.43%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 14.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 14.29%
Migraine Without Aura (headache without neurological problems): 2 people, 14.29%
Impaired Gastric Emptying: 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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