Cresemba and Flonase drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cresemba (isavuconazonium sulfate) and Flonase (fluticasone propionate). Common drug interactions include death among females and fungal infection among males.
The phase IV clinical study analyzes what interactions people have when they take Cresemba and Flonase. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Cresemba?
Cresemba has active ingredients of isavuconazonium sulfate. eHealthMe is studying from 2,574 Cresemba users. Check the latest studies of Cresemba.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
37 people who take Cresemba and Flonase together, and have interactions are studied.

What are the common drug interactions of Cresemba and Flonase, by gender? *:
female:
- Death
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Dyspnoea (difficult or laboured respiration)
- Eosinophil count decreased
- Gait disturbance
- Gastric mucosal lesion (lesion of stomach mucous membrane)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Haemochromatosis (body to absorb more iron than usual from food)
- Headache (pain in head)
- Hyperglycaemia (high blood sugar)
male:
- Fungal infection
- Drug ineffective
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Acute respiratory failure
- Anxiety
- Back pain
- Blood glucose increased
- Blood pressure increased
- Confusional state
- Constipation
What are the common drug interactions of Cresemba and Flonase, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Decreased appetite
- Dehydration (dryness resulting from the removal of water)
- Lung transplant rejection (failure of lung transplant)
- Tenderness (pain or discomfort when an affected area is touched)
30-39:
- Pneumonia
40-49:
- Acute respiratory failure
- Febrile neutropenia (fever with reduced white blood cells)
- Pancreatitis acute (sudden inflammation of pancreas)
- Pneumonia
- Thrombocytopenia (decrease of platelets in blood)
50-59:
- Cystic fibrosis (disease of the secretary glands)
- Pneumonia
- Intestinal obstruction
- Oral discomfort (pain or irritation in mouth)
- Pain in extremity
- Pneumonia bacterial (pneumonia associated with bacterial infection)
60+:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Nausea (feeling of having an urge to vomit)
- Anxiety
- Back pain
- Blood glucose increased
- Blood pressure increased
- Confusional state
- Constipation
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Deafness
What are the existing conditions these people have? *
- Cystic Fibrosis (disease of the secretary glands): 11 people, 29.73%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 18.92%
- Pain: 6 people, 16.22%
- Nausea (feeling of having an urge to vomit): 5 people, 13.51%
- Insomnia (sleeplessness): 5 people, 13.51%
- Nausea And Vomiting: 4 people, 10.81%
- Hypersensitivity: 4 people, 10.81%
- Renal Cell Carcinoma (a kidney cancer): 3 people, 8.11%
- Pain In Extremity: 3 people, 8.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
* Approximation only. Some reports may have incomplete information.
Do you take Cresemba and Flonase?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cresemba and Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cresemba:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cresemba and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on isavuconazonium sulfate and fluticasone propionate (the active ingredients of Cresemba and Flonase, respectively), and Cresemba and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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