Dexrazoxane and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexrazoxane (dexrazoxane hydrochloride) and Acetaminophen (acetaminophen). Common drug interactions include neutrophil count decreased among females and pathological fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Dexrazoxane and Acetaminophen. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Dexrazoxane?

Dexrazoxane has active ingredients of dexrazoxane hydrochloride. eHealthMe is studying from 1,141 Dexrazoxane users. Check the latest studies of Dexrazoxane.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.



On Jul, 18, 2026

26 people who take Dexrazoxane and Acetaminophen together, and have interactions are studied.

Dexrazoxane and Acetaminophen drug interactions.

What are the common drug interactions of Dexrazoxane and Acetaminophen, by gender? *:

female:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Left ventricular dysfunction
  3. Pulmonary hypertension (increase in blood pressure in the lung artery)
  4. Abdominal pain
  5. Nausea (feeling of having an urge to vomit)
  6. Arrhythmia (irregular heartbeat)
  7. Anaemia (lack of blood)
  8. Anal abscess
  9. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  10. Hypokalaemia (low potassium)

male:

  1. Pathological fracture (broken bone caused by disease)
  2. Diarrhoea
  3. Leukopenia (less number of white blood cells in blood)
  4. Mucosal inflammation (infection of mucous membrane)
  5. Nausea (feeling of having an urge to vomit)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Oedema peripheral (superficial swelling)
  8. Petechiae (a small red or purple spot caused by bleeding into the skin)
  9. Platelet count decreased
  10. Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Dexrazoxane and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  3. Blood culture positive
  4. Depressed level of consciousness
  5. Excessive eye blinking (excessive blinking is dry eyes)
  6. Febrile neutropenia (fever with reduced white blood cells)
  7. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  8. Pneumonia fungal
  9. Pyrexia (fever)
  10. Staring (a prolonged gaze or fixed look)

10-19:

  1. Hypertension (high blood pressure)
  2. Platelet count decreased
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Abdominal pain
  5. Abdominal pain upper
  6. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  7. Arthralgia (joint pain)
  8. Back pain
  9. Cholecystitis (infection of gallbladder)
  10. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Abdominal pain
  3. Nausea (feeling of having an urge to vomit)
  4. Anaemia (lack of blood)
  5. Anal abscess
  6. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  7. Hypokalaemia (low potassium)
  8. Neutropenia (an abnormally low number of neutrophils)

60+:

  1. Pathological fracture (broken bone caused by disease)
  2. Diarrhoea
  3. Epistaxis (bleed from the nose)
  4. Leukopenia (less number of white blood cells in blood)
  5. Mucosal inflammation (infection of mucous membrane)
  6. Nausea (feeling of having an urge to vomit)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Oedema peripheral (superficial swelling)
  9. Petechiae (a small red or purple spot caused by bleeding into the skin)
  10. Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 19.23%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 15.38%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 11.54%
  4. Febrile Neutropenia (fever with reduced white blood cells): 3 people, 11.54%
  5. Breast Cancer: 3 people, 11.54%
  6. Urination - Excessive Volume: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Dexrazoxane and Acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dexrazoxane and Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dexrazoxane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexrazoxane and drugs from A to Z:

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Browse all interactions between Acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dexrazoxane hydrochloride and acetaminophen (the active ingredients of Dexrazoxane and Acetaminophen, respectively), and Dexrazoxane and Acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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