Dilaudid and Aventyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dilaudid (hydromorphone hydrochloride) and Aventyl (nortriptyline hydrochloride). Common drug interactions include intestinal obstruction among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Dilaudid and Aventyl. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Aventyl?

Aventyl has active ingredients of nortriptyline hydrochloride. eHealthMe is studying from 515 Aventyl users. Check the latest studies of Aventyl.

On Jul, 13, 2026

25 people who take Dilaudid and Aventyl together, and have interactions are studied.

What are the common drug interactions of Dilaudid and Aventyl, by gender? *:

female:

Intestinal obstruction
Diarrhoea
Nausea (feeling of having an urge to vomit)
Abdominal pain
Abdominal pain upper
Anxiety
Fibromyalgia (a long-term condition which causes pain all over the body)
Haematochezia (passage of stools containing blood)
Headache (pain in head)
Mucous stools (mucous with stool)

male:

Abdominal distension
Abdominal pain
Hyperhidrosis (abnormally increased sweating)
Rash
Skin irritation
Stress
Weight fluctuation
Acne (skin problems that cause pimples)
Anal abscess
Anxiety

What are the common drug interactions of Dilaudid and Aventyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Anxiety
Haematochezia (passage of stools containing blood)
Intestinal obstruction
Stress
Abdominal pain upper
Diarrhoea
Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)
Mucous stools (mucous with stool)

40-49:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Chest pain
Dark circles under eyes
Diplopia (double vision)
Dizziness
Dysarthria (speech disorder)
Eyelid ptosis (falling of the upper or lower eyelid)
Head discomfort
Hemiparesis (weakness on one side of the body)
Hospitalisation

50-59:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anaemia (lack of blood)
Depression
Gait disturbance
Grip strength decreased
Gun shot wound
Hip arthroplasty
Hospitalisation
Hypokalaemia (low potassium)
Lung disorder (lung disease)

60+:

Asthenia (weakness)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Therapeutic response decreased (less preventive response)
Gait disturbance
Grip strength decreased
Hip arthroplasty
Hypotension (abnormally low blood pressure)
Lung disorder (lung disease)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 48.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.00%
Migraine (headache): 3 people, 12.00%
Guillain-Barre Syndrome (the body's immune system attacks its peripheral nervous system): 2 people, 8.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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