Diprivan and Xarelto drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprivan (propofol) and Xarelto (rivaroxaban). Common drug interactions include mania among females and mania among males.

The phase IV clinical study analyzes what interactions people have when they take Diprivan and Xarelto. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

On Aug, 12, 2026

30 people who take Diprivan and Xarelto together, and have interactions are studied.

What are the common drug interactions of Diprivan and Xarelto, by gender? *:

female:

Mania (a state of abnormally elevated or irritable mood)
Cardiac arrest
Renal failure (kidney dysfunction)
Drug resistance (reduction in effectiveness of a drug)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Abdominal infection
Altered state of consciousness (altered state of mind)
Ascites (accumulation of fluid in the abdominal cavity)
Chronic kidney disease
Diplopia (double vision)

male:

Mania (a state of abnormally elevated or irritable mood)
Knee arthroplasty
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Monoplegia (a paralysis of a single limb)
Mood altered (changes in mood)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Pneumonia
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Infection

What are the common drug interactions of Diprivan and Xarelto, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cardiac arrest
Chronic kidney disease
Epistaxis (bleed from the nose)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

Knee arthroplasty
Post procedural haemorrhage (post procedural bleeding)
Thrombocytopenia (decrease of platelets in blood)
Abscess limb (limb infection)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Infection
Post-traumatic stress disorder

60+:

Mania (a state of abnormally elevated or irritable mood)
Pneumonia
Mood altered (changes in mood)
Renal failure (kidney dysfunction)
Drug resistance (reduction in effectiveness of a drug)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Abdominal infection
Allergy test positive
Altered state of consciousness (altered state of mind)
Ascites (accumulation of fluid in the abdominal cavity)

What are the existing conditions these people have? *

Haemorrhage (bleeding): 10 people, 33.33%
Anaesthesia: 9 people, 30.00%
Procedural Vomiting: 8 people, 26.67%
Sedation: 4 people, 13.33%
High Blood Pressure: 3 people, 10.00%
Diabetes: 3 people, 10.00%
Weight Decreased: 2 people, 6.67%
Type 2 Diabetes: 2 people, 6.67%
Pain: 2 people, 6.67%
Nausea (feeling of having an urge to vomit): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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