Edoxaban and Rivaroxaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Edoxaban (edoxaban) and Rivaroxaban (rivaroxaban). Common drug interactions include confusional state among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Edoxaban and Rivaroxaban. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Edoxaban?

Edoxaban has active ingredients of edoxaban. eHealthMe is studying from 1,783 Edoxaban users. Check the latest studies of Edoxaban.

What is Rivaroxaban?

Rivaroxaban has active ingredients of rivaroxaban. It is often used in blood clots. eHealthMe is studying from 26,543 Rivaroxaban users. Check the latest studies of Rivaroxaban.

On Jul, 11, 2026

39 people who take Edoxaban and Rivaroxaban together, and have interactions are studied.

Edoxaban and Rivaroxaban drug interactions.

What are the common drug interactions of Edoxaban and Rivaroxaban, by gender? *:

female:

Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Death
Delirium (wild excitement)
Drug intolerance (drug sensitivity)
Hallucination (an experience involving the perception of something not present)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)
Urinary tract infection

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
Epistaxis (bleed from the nose)
Melaena (the passage of black, tarry stools)
Abdominal infection
Abdominal pain
Anaemia (lack of blood)
Cardiac failure
Diarrhoea
Gastric ulcer perforation (stomach hole due to ulcer)

What are the common drug interactions of Edoxaban and Rivaroxaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Intermenstrual bleeding

50-59:

n/a

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
Hypersensitivity
Contusion (a type of hematoma of tissue in which capillaries)
Death
Drug intolerance (drug sensitivity)
Epistaxis (bleed from the nose)
Melaena (the passage of black, tarry stools)
Uterine haemorrhage (uterine bleeding)
Abdominal infection

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 18 people, 46.15%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 12.82%
Acute Myocardial Infarction (acute heart attack): 4 people, 10.26%
Ill-Defined Disorder: 3 people, 7.69%
High Blood Pressure: 3 people, 7.69%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 7.69%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 5.13%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.13%
High Blood Cholesterol: 2 people, 5.13%
Heart Attack: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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