Effexor and Azilect drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Azilect (rasagiline mesylate). Common drug interactions include fatigue among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Azilect. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Azilect?

Azilect has active ingredients of rasagiline mesylate. It is often used in parkinson's disease. eHealthMe is studying from 8,622 Azilect users. Check the latest studies of Azilect.



On Jul, 07, 2026

68 people who take Effexor and Azilect together, and have interactions are studied.

Effexor and Azilect drug interactions.

What are the common drug interactions of Effexor and Azilect, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Haemorrhage intracranial (bleeding within the skull)
  3. Hallucination, olfactory (sensations of smelling something that is actually not there)
  4. Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
  5. Hypersexuality
  6. Intussusception
  7. Libido increased (increased sexual urge to have sex)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  10. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)

male:

  1. Fatigue (feeling of tiredness)
  2. Hypokinesia (decreased bodily movement)
  3. Impaired driving ability
  4. Arrhythmia (irregular heartbeat)
  5. Death
  6. Dyskinesia (abnormality or impairment of voluntary movement)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Hypersomnia (excessive daytime sleepiness (eds))
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the common drug interactions of Effexor and Azilect, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dystonia (abnormal muscle tone)
  2. Hallucination (an experience involving the perception of something not present)

50-59:

  1. Pyrexia (fever)
  2. Sinusitis (inflammation of sinus)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Thrombosis (formation of a blood clot inside a blood vessel)
  5. Asthenia (weakness)
  6. Dyskinesia (abnormality or impairment of voluntary movement)
  7. Hypokinesia (decreased bodily movement)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Abdominal discomfort
  10. Abdominal pain

60+:

  1. Fall
  2. Fatigue (feeling of tiredness)
  3. Hypertension (high blood pressure)
  4. Confusional state
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Rash
  8. Abnormal behaviour
  9. Abnormal dreams
  10. Aggression

What are the existing conditions these people have? *

  1. Stress And Anxiety: 12 people, 17.65%
  2. Hallucinations (sensations that appear real but are created by your mind): 8 people, 11.76%
  3. Pain: 7 people, 10.29%
  4. High Blood Pressure: 7 people, 10.29%
  5. Sleep Disorder: 6 people, 8.82%
  6. Delusion (a false belief or opinion): 6 people, 8.82%
  7. Constipation: 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Effexor and Azilect:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azilect:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azilect and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride and rasagiline mesylate (the active ingredients of Effexor and Azilect, respectively), and Effexor and Azilect (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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