Effient and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effient (prasugrel hydrochloride) and Glucophage (metformin hydrochloride). Common drug interactions include balance disorder among females and angina unstable among males.

The phase IV clinical study analyzes what interactions people have when they take Effient and Glucophage. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

56 people who take Effient and Glucophage together, and have interactions are studied.

Effient and Glucophage drug interactions.

What are the common drug interactions of Effient and Glucophage, by gender? *:

female:

Balance disorder
Bone density decreased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Death
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dizziness
Drug ineffective
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)

male:

Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Adenocarcinoma pancreas (cancer of pancreas)
Blood glucose increased
Blood urea increased
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cough
Dizziness

What are the common drug interactions of Effient and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug hypersensitivity
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Rectal haemorrhage (bleeding from anus)

50-59:

Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hypertension (high blood pressure)
Injection site bruising
Injection site pain
Memory impairment
Metastases to liver (cancer spreads to liver)
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Stress
Tooth fracture

60+:

Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Dizziness
Blood pressure systolic increased
Blood urea increased
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug ineffective

What are the existing conditions these people have? *

High Blood Cholesterol: 8 people, 14.29%
High Blood Pressure: 7 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 12.50%
Blood Pressure Abnormal: 7 people, 12.50%
Thyroid Diseases: 6 people, 10.71%
Cardiac Disorder: 6 people, 10.71%
Chest Pain: 5 people, 8.93%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 7.14%
Type 2 Diabetes: 4 people, 7.14%
Stress And Anxiety: 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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