Effient and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effient (prasugrel hydrochloride) and Profen (ibuprofen). Common drug interactions include sinusitis among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Effient and Profen. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 07, 2026

84 people who take Effient and Profen together, and have interactions are studied.

What are the common drug interactions of Effient and Profen, by gender? *:

female:

Sinusitis (inflammation of sinus)
Chronic kidney disease
Renal failure (kidney dysfunction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Chest pain
Coronary artery stenosis (narrowing of coronary artery)
Nasal discharge discolouration (change in colour of nasal discharge)
Nausea (feeling of having an urge to vomit)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Tongue discolouration (colour change of tongue)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Chronic kidney disease
Suicidal ideation
Suicide attempt
Therapeutic response unexpected
Arrhythmia (irregular heartbeat)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anxiety

What are the common drug interactions of Effient and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arrhythmia (irregular heartbeat)
Atrial thrombosis (blood clot that develops in an artery)
Blood triglycerides increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Cardiovascular disorder (heart diseases)

50-59:

Blood triglycerides increased
Cardiomyopathy (weakening of the heart muscle)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspepsia (indigestion)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertension (high blood pressure)
Jaundice cholestatic
Lung neoplasm malignant (cancer tumour of lung)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac disorder
Gastric cancer stage iv (cancer cells have spread to distant organs)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hot flush (sudden feelings of heat)
Night sweats (sweating in night)
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Blood calcium increased

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 22 people, 26.19%
High Blood Pressure: 22 people, 26.19%
High Blood Cholesterol: 19 people, 22.62%
Diabetes: 14 people, 16.67%
Cardiac Disorder: 12 people, 14.29%
Depression: 11 people, 13.10%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 11.90%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 11.90%
Stress And Anxiety: 8 people, 9.52%
Headache (pain in head): 8 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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