Elavil and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elavil (amitriptyline hydrochloride) and Actigall (ursodiol). Common drug interactions include dysphagia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Elavil and Actigall. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

On Jul, 12, 2026

31 people who take Elavil and Actigall together, and have interactions are studied.

What are the common drug interactions of Elavil and Actigall, by gender? *:

female:

Dysphagia (a condition in which swallowing is difficult or painful)
Electrocardiogram qt prolonged
Haematocrit decreased
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hepatic fibrosis (scarring process that represents the liver's response to injury)
Iron deficiency
Memory impairment
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)

male:

Pain
Ankle fracture
Colon cancer
Cough
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Increased upper airway secretion
Joint dislocation (a joint position is changed from normal position)
Local swelling (swelling at the site of some application of substance or injury)
Oropharyngeal pain

What are the common drug interactions of Elavil and Actigall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Inflammatory bowel disease
Drug toxicity
Hypotension (abnormally low blood pressure)
Oedema (fluid collection in tissue)
Photophobia (extreme sensitivity to light)
Pyrexia (fever)
Thrombosis (formation of a blood clot inside a blood vessel)

20-29:

Pneumonia
Abdominal pain
Anaemia (lack of blood)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Constipation
Diarrhoea
Electrocardiogram qt prolonged
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Iron deficiency
Malaise (a feeling of general discomfort or uneasiness)

30-39:

Abdominal pain upper
Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Blood creatinine increased
Blood glucose decreased
Blood urea increased
Chest discomfort
Clumsiness (a lack of coordination or elegance)

40-49:

Skin hypertrophy (skin cells enlarges)
Skin induration (an abnormally hard spot or area on the skin)
Skin lesion
Skin plaque (red, scaly patches to appear on the skin)
Swelling
Anxiety
Arthralgia (joint pain)
Bone pain
Dermatosis (a disease of the skin, esp. one that does not cause inflammation)
Emotional distress

50-59:

Ankle fracture
Cellulitis (infection under the skin)
Fall
Lower limb fracture
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Joint effusion (presence of extra fluid in joint covering)
Joint dislocation (a joint position is changed from normal position)

60+:

Diarrhoea
Acute myocardial infarction (acute heart attack)
Fall
Fatigue (feeling of tiredness)
Fistula (an abnormal connection or passageway between two)
Gallbladder disorder
Injury
Local swelling (swelling at the site of some application of substance or injury)
Lower respiratory tract infection
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 22.58%
Nausea (feeling of having an urge to vomit): 3 people, 9.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.68%
Cough: 3 people, 9.68%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 9.68%
Thyroid Diseases: 2 people, 6.45%
Sleep Disorder: 2 people, 6.45%
Sinusitis (inflammation of sinus): 2 people, 6.45%
Nuclear Magnetic Resonance Imaging Abdominal: 2 people, 6.45%
Joint Swelling: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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