Acetaminophen and codeine phosphate and Xanax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate) and Xanax (alprazolam). Common drug interactions include lipids increased among females and fanconi syndrome acquired among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and codeine phosphate and Xanax. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

On Jul, 12, 2026

34 people who take Acetaminophen and codeine phosphate and Xanax together, and have interactions are studied.

Acetaminophen and codeine phosphate and Xanax drug interactions.

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Xanax, by gender? *:

female:

Lipids increased (excess lipid in body)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Multiple drug overdose intentional
Muscle atrophy (a decrease in the mass of the muscle)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

male:

Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Renal failure (kidney dysfunction)
Hyperphagia (an abnormal appetite for food)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Injury
Lipase increased
Morbid thoughts (serious thoughts)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Overdose
Pathological gambling

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Xanax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Respiratory depression (respiration has a rate below 12 breaths)
Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

Sedation
Overdose
Completed suicide (act of taking one's own life)
Death
Drug dependence
Drug level increased
Loss of consciousness

30-39:

n/a

40-49:

Bradypnoea (an abnormally slow respiratory rate)
Sopor (sleep)
Abdominal pain lower
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Overdose
Completed suicide (act of taking one's own life)
Intentional self-injury
Abdominal pain
Anal fissure
Angina pectoris (chest pain due to ischemia of the heart muscle)

50-59:

Depression
Diarrhoea haemorrhagic (bloody diarrhoea)
Hallucination (an experience involving the perception of something not present)
Lipase increased
Morbid thoughts (serious thoughts)
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Suicidal ideation
Tremor (trembling or shaking movements in one or more parts of your body)

60+:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood cholesterol increased
Blood creatinine increased
Cardiac failure
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 14.71%
Depression: 5 people, 14.71%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 4 people, 11.76%
Insomnia (sleeplessness): 4 people, 11.76%
Venous Insufficiency (poor circulation of blood caused by damaged or enlarged veins): 3 people, 8.82%
Hepatitis B: 3 people, 8.82%
Enlarged Prostate: 3 people, 8.82%
Cardiac Failure: 3 people, 8.82%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 8.82%
Arrhythmias (irregular heartbeat): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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