Estradiol and Aciphex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estradiol (estradiol) and Aciphex (rabeprazole sodium). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Estradiol and Aciphex. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

On Jul, 18, 2026

63 people who take Estradiol and Aciphex together, and have interactions are studied.

Estradiol and Aciphex drug interactions.

What are the common drug interactions of Estradiol and Aciphex, by gender? *:

female:

Pain
Fatigue (feeling of tiredness)
Breast cancer female
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Impaired healing
Infusion site erythema (reddening of the skin at infusion site)
Infusion site inflammation
Infusion site swelling
Diarrhoea
Fall

male:

n/a

What are the common drug interactions of Estradiol and Aciphex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Bronchial hyperreactivity
Cellulitis (infection under the skin)
Dermatophytosis (inflammation of the skin and underlying muscle tissue)
Dyspepsia (indigestion)
Emotional disorder
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Gout (uric acid crystals building up in the body)

30-39:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Dyspnoea (difficult or laboured respiration)
Gastroenteritis salmonella (inflammation of stomach and intestine caused by salmonella bacteria)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Nervousness
Somnolence (a state of near-sleep, a strong desire for sleep)
Throat tightness
Vertigo
Vomiting

40-49:

Chest pain
Breast cancer female
Impaired healing
Drug ineffective
Migraine (headache)
Emotional disorder
Hot flush (sudden feelings of heat)
Oestrogen receptor assay positive
Pain
Anxiety

50-59:

Rash erythematous (redness of the skin)
Serum ferritin increased
Abdominal discomfort
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atelectasis (partial or complete collapse of the lung)
Bladder discomfort
Blood cholesterol increased
Blood iron increased

60+:

Fatigue (feeling of tiredness)
Pain
Weight decreased
Weight increased
Asthenia (weakness)
Back pain
Breast pain
Breast tenderness
Chills (felling of cold)
Loss of consciousness

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 12.70%
Pain: 8 people, 12.70%
Depression: 8 people, 12.70%
High Blood Pressure: 7 people, 11.11%
Stress And Anxiety: 6 people, 9.52%
Immunodeficiency Common Variable: 6 people, 9.52%
Asthma: 6 people, 9.52%
Nausea (feeling of having an urge to vomit): 4 people, 6.35%
Muscle Spasms (muscle contraction): 4 people, 6.35%
High Blood Cholesterol: 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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