Ethyol and Neupogen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ethyol (amifostine) and Neupogen (filgrastim). Common drug interactions include vomiting among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Ethyol and Neupogen. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Ethyol?
Ethyol has active ingredients of amifostine. eHealthMe is studying from 1,484 Ethyol users. Check the latest studies of Ethyol.
What is Neupogen?
Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.
32 people who take Ethyol and Neupogen together, and have interactions are studied.

What are the common drug interactions of Ethyol and Neupogen, by gender? *:
female:
- Vomiting
- White blood cell count decreased
- Anaemia (lack of blood)
- Burning sensation
- Dehydration (dryness resulting from the removal of water)
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
- Discomfort
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Herpes simplex (herpes simplex is a common viral infection)
male:
- Pyrexia (fever)
- Fatigue (feeling of tiredness)
- Diarrhoea
- Hypokalaemia (low potassium)
- Localised infection (infection at the single location)
- Malaise (a feeling of general discomfort or uneasiness)
- Pharyngolaryngeal pain
- Rash generalised (rash on most of body parts)
- Skin exfoliation (removal of the oldest dead skin cells)
- Abdominal strangulated hernia (abdominal blood supply damaged hernia)
What are the common drug interactions of Ethyol and Neupogen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Blood creatinine increased
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
- Diarrhoea
- Glomerular filtration rate decreased
- Hypotension (abnormally low blood pressure)
- Implant infection (infection at implant site)
- Inflammation
- Labile blood pressure (wildly fluctuating blood pressure)
- Oedema (fluid collection in tissue)
10-19:
n/a
20-29:
n/a
30-39:
- Blood bilirubin increased
- Rash pruritic (redness with itching)
- Respiratory distress (difficulty in breathing)
- Rigors (an episode of shaking or exaggerated shivering)
40-49:
n/a
50-59:
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypoaesthesia (reduced sense of touch or sensation)
- Incision site erythema (redness of the skin at incision site)
- Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
- Injection site urticaria (rash of round, red welts on the skin at injection site)
- Insomnia (sleeplessness)
- Lymphoedema (localized fluid retention and tissue swelling)
- Nausea (feeling of having an urge to vomit)
- Pain
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
60+:
- Fatigue (feeling of tiredness)
- Asthenia (weakness)
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
- Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
- Herpes simplex (herpes simplex is a common viral infection)
- Hypersensitivity
- Injection site reaction
- Localised infection (infection at the single location)
- Mycoplasma infection (bacterial infection)
What are the existing conditions these people have? *
- Adverse Drug Reaction: 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Ethyol and Neupogen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ethyol and Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ethyol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ethyol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neupogen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amifostine and filgrastim (the active ingredients of Ethyol and Neupogen, respectively), and Ethyol and Neupogen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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