Flexeril and Adenosine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Adenosine (adenosine). Common drug interactions include anxiety among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Adenosine. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Adenosine?

Adenosine has active ingredients of adenosine. eHealthMe is studying from 2,711 Adenosine users. Check the latest studies of Adenosine.

On Jul, 18, 2026

14 people who take Flexeril and Adenosine together, and have interactions are studied.

Flexeril and Adenosine drug interactions.

What are the common drug interactions of Flexeril and Adenosine, by gender? *:

female:

Anxiety
Fatigue (feeling of tiredness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Appetite disorder (abnormal eating habits)
Confusional state
Dizziness
Drug hypersensitivity
Foot fracture
Intervertebral disc degeneration (spinal disc degeneration)
Malaise (a feeling of general discomfort or uneasiness)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Procedural pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicide attempt
Surgery
Visual impairment
Chronic kidney disease
Emotional distress
Pain

What are the common drug interactions of Flexeril and Adenosine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Foot fracture
Intervertebral disc degeneration (spinal disc degeneration)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Vitamin b12 deficiency
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

50-59:

Anxiety
Appetite disorder (abnormal eating habits)
Eructation (release of gas from the digestive tract)
Flushing (the warm, red condition of human skin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Procedural pain
Restlessness (not able to rest)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Suicide attempt

60+:

n/a

What are the existing conditions these people have? *

Hiv Infection: 6 people, 42.86%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 35.71%
High Blood Cholesterol: 4 people, 28.57%
Depression: 4 people, 28.57%
Cardiac Disorder: 2 people, 14.29%
Insomnia (sleeplessness): 2 people, 14.29%
Diabetes: 2 people, 14.29%
Menopause (end of monthly cycles in women): 2 people, 14.29%
Morbid Thoughts (serious thoughts): 2 people, 14.29%
Night Sweats (sweating in night): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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