Flexeril and Verapamil hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Verapamil hcl (verapamil hydrochloride). Common drug interactions include haemoglobin decreased among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Verapamil hcl. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Verapamil hcl?

Verapamil hcl has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,807 Verapamil hcl users. Check the latest studies of Verapamil hcl.

On Jul, 12, 2026

34 people who take Flexeril and Verapamil hcl together, and have interactions are studied.

Flexeril and Verapamil hcl drug interactions.

What are the common drug interactions of Flexeril and Verapamil Hcl, by gender? *:

female:

Haemoglobin decreased
Hallucination (an experience involving the perception of something not present)
Hyperhidrosis (abnormally increased sweating)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Injection site erythema (redness at injection site)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Ligament sprain (ligament stretched)
Malaise (a feeling of general discomfort or uneasiness)
Melaena (the passage of black, tarry stools)

male:

Asthma
Cataract (clouding of the lens inside the eye)
Increased viscosity of bronchial secretion
Insomnia (sleeplessness)
Joint swelling
Lacrimation increased
Multiple allergies (allergy to multiple agents)
Peripheral swelling
Productive cough
Respiratory disorder (respiratory disease)

What are the common drug interactions of Flexeril and Verapamil Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Vaginal haemorrhage (vaginal bleeding)

40-49:

Enthesopathy (disorder of entheses (bone attachments))
Essential hypertension (primary hypertension)
Eustachian tube disorder (inflammation of the middle ear, commonly affects the eustachian tube)
Gastritis (inflammation of stomach)
Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum)
Gastroenteritis (inflammation of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Haematuria (presence of blood in urine)
Hypoglycaemia (deficiency of glucose in the bloodstream)

50-59:

Drug hypersensitivity
Drug ineffective
Fatigue (feeling of tiredness)
Joint swelling
Arthralgia (joint pain)
Asthma
Burning sensation
Cough
Disability
Drug administration error

60+:

Cardiac arrest
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Atrophy (wasting away of a part of the body)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Calcinosis (calcium deposits in any soft tissue)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Chest pain

What are the existing conditions these people have? *

Back Pain: 5 people, 14.71%
Depression: 5 people, 14.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.76%
Intervertebral Disc Degeneration (spinal disc degeneration): 3 people, 8.82%
Lipids Abnormal: 3 people, 8.82%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 8.82%
Insomnia (sleeplessness): 3 people, 8.82%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 8.82%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.82%
Oedema Peripheral (superficial swelling): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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