Flonase and Pegintron drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flonase (fluticasone propionate) and Pegintron (peginterferon alfa-2b). Common drug interactions include fatigue among females and dysgeusia among males.
The phase IV clinical study analyzes what interactions people have when they take Flonase and Pegintron. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
What is Pegintron?
Pegintron has active ingredients of peginterferon alfa-2b. It is often used in hepatitis c. eHealthMe is studying from 10,326 Pegintron users. Check the latest studies of Pegintron.
11 people who take Flonase and Pegintron together, and have interactions are studied.

What are the common drug interactions of Flonase and Pegintron, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Red blood cell count decreased
- Erythema (redness of the skin)
- Influenza like illness
- Injection site rash
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Nausea (feeling of having an urge to vomit)
- Pain in extremity
male:
- Dysgeusia (disorder of the sense of taste)
- Fatigue (feeling of tiredness)
- Dry mouth
- Dyspepsia (indigestion)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhage (bleeding)
- Influenza like illness
- Injection site irritation
- Injection site rash
What are the common drug interactions of Flonase and Pegintron, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dysgeusia (disorder of the sense of taste)
- Fatigue (feeling of tiredness)
- Feeling hot
- Flushing (the warm, red condition of human skin)
- Hyperhidrosis (abnormally increased sweating)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Nausea (feeling of having an urge to vomit)
- Oropharyngeal pain
- Pain
- Pharyngeal disorder
30-39:
n/a
40-49:
- Red blood cell count decreased
- Fatigue (feeling of tiredness)
- Injection site rash
50-59:
- Fatigue (feeling of tiredness)
- Dysgeusia (disorder of the sense of taste)
- Dry mouth
- Dyspepsia (indigestion)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhage (bleeding)
- Injection site irritation
- Injection site rash
- Mouth ulceration (mouth ulcers)
60+:
n/a
What are the existing conditions these people have? *
- Night Sweats (sweating in night): 1 person, 9.09%
- Hypersensitivity: 1 person, 9.09%
- Hot Flush (sudden feelings of heat): 1 person, 9.09%
- High Blood Pressure: 1 person, 9.09%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
- Depression: 1 person, 9.09%
- Cough: 1 person, 9.09%
- Anaemia (lack of blood): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Flonase and Pegintron?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flonase and Pegintron:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pegintron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pegintron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluticasone propionate and peginterferon alfa-2b (the active ingredients of Flonase and Pegintron, respectively), and Flonase and Pegintron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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