Florinef and Dilaudid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Dilaudid (hydromorphone hydrochloride). Common drug interactions include renal impairment among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Dilaudid. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

On Jul, 10, 2026

52 people who take Florinef and Dilaudid together, and have interactions are studied.

Florinef and Dilaudid drug interactions.

What are the common drug interactions of Florinef and Dilaudid, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Abdominal distension
Adenocarcinoma pancreas (cancer of pancreas)
Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
Axillary vein thrombosis (formation of a blood clot in axillary vein)
Bacteraemia (presence of bacteria in the blood)
Blood bicarbonate decreased

male:

Confusional state
Dehydration (dryness resulting from the removal of water)
Weight decreased
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fear
Loss of consciousness
Somnolence (a state of near-sleep, a strong desire for sleep)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Bk virus infection

What are the common drug interactions of Florinef and Dilaudid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fibromyalgia (a long-term condition which causes pain all over the body)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hypercoagulation (increased tendency for clotting of the blood)
Neuralgia (pain in one or more nerves)
Suicidal ideation
Drug hypersensitivity
Blood bicarbonate decreased
Blood chloride increased
Device related infection
Drug ineffective

30-39:

n/a

40-49:

Abdominal pain
Arthralgia (joint pain)
Blood pressure orthostatic
Diarrhoea
Fluid imbalance (imbalance of fluid in body in intake and fluid lost)
Hypokalaemia (low potassium)
Insulin-like growth factor increased
Intestinal obstruction
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Overdose

50-59:

Immunodeficiency
Immunosuppressant drug level increased
Incontinence (lack of moderation or self-control)
Infection
Injection site bruising
Intestinal obstruction
Intestinal polyp (small growths in the bowel with the potential for further growth)
Intestinal resection
Large intestinal ulcer
Leukopenia (less number of white blood cells in blood)

60+:

Confusional state
Dehydration (dryness resulting from the removal of water)
Loss of consciousness
Somnolence (a state of near-sleep, a strong desire for sleep)
Haemorrhage (bleeding)
Abnormal dreams
Anaemia (lack of blood)
Asthenia (weakness)
Clostridial infection (infectious conditions by clostridium bacteria)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

What are the existing conditions these people have? *

Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright): 8 people, 15.38%
Birth Control: 8 people, 15.38%
Stress And Anxiety: 5 people, 9.62%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 9.62%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 9.62%
Tumor: 3 people, 5.77%
Thyroid Diseases: 3 people, 5.77%
High Blood Pressure: 3 people, 5.77%
Diabetes: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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