Floxin and Valtrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Floxin (ofloxacin) and Valtrex (valacyclovir hydrochloride). Common drug interactions include urinary tract infection among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Floxin and Valtrex. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.



On Jul, 10, 2026

14 people who take Floxin and Valtrex together, and have interactions are studied.

Floxin and Valtrex drug interactions.

What are the common drug interactions of Floxin and Valtrex, by gender? *:

female:

  1. Urinary tract infection
  2. Anxiety
  3. Balance disorder
  4. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  5. Breast cancer recurrent
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  8. Constipation
  9. Cyst (a closed sac)
  10. Dental caries

male:

  1. Urinary tract infection
  2. Dizziness
  3. Skin infection
  4. Streptococcal sepsis (whole body inflammation by streptococcal)
  5. Eustachian tube obstruction (blockage of the eustachian tube)
  6. Fatigue (feeling of tiredness)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Hypoacusis (loss of hearing)
  9. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  10. Pneumonia

What are the common drug interactions of Floxin and Valtrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Eustachian tube obstruction (blockage of the eustachian tube)
  2. Hypoacusis (loss of hearing)
  3. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  4. Post procedural complication

60+:

  1. Urinary tract infection
  2. Pneumonia
  3. Dental caries
  4. Diarrhoea
  5. Dysgeusia (disorder of the sense of taste)
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Endometrial disorder
  8. Fall
  9. Gingival swelling (gums swelling)
  10. Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)

What are the existing conditions these people have? *

  1. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 35.71%
  2. Constipation: 5 people, 35.71%
  3. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 28.57%
  4. Multiple Myeloma (cancer of the plasma cells): 2 people, 14.29%
  5. Urinary Tract Infection: 1 person, 7.14%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Floxin and Valtrex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Floxin and Valtrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valtrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Floxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valtrex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ofloxacin and valacyclovir hydrochloride (the active ingredients of Floxin and Valtrex, respectively), and Floxin and Valtrex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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