Fluconazole and Azopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Azopt (brinzolamide). Common drug interactions include renal failure among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Azopt. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

On Jul, 16, 2026

39 people who take Fluconazole and Azopt together, and have interactions are studied.

Fluconazole and Azopt drug interactions.

What are the common drug interactions of Fluconazole and Azopt, by gender? *:

female:

Renal failure (kidney dysfunction)
Asthenia (weakness)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Multiple myeloma (cancer of the plasma cells)
Renal failure acute (rapid kidney dysfunction)
Alanine aminotransferase increased
Angioedema (rapid swelling of the dermis)
Aspartate aminotransferase increased
Blood chloride increased

male:

Diarrhoea
Dizziness
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Balance disorder
Biliary dilatation
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
Bone pain
Carcinoid syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction)

What are the common drug interactions of Fluconazole and Azopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood chloride increased
Blood creatinine increased
Blood glucose increased
Blood magnesium increased
Blood sodium increased
Blood urea increased
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Confusional state

50-59:

Retinopathy (acute damage to the retina of the eye)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Nephrogenic anaemia (anaemia due to kidney disease)
Sepsis (a severe blood infection that can lead to organ failure and death)
Angioedema (rapid swelling of the dermis)
Hypersensitivity
Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

60+:

Diarrhoea
Aphasia (damage to the parts of the brain that control language)
Anaemia vitamin b12 deficiency
Anxiety
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Balance disorder
Biliary dilatation
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 17.95%
Pain: 6 people, 15.38%
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 5 people, 12.82%
Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 5 people, 12.82%
Bone Marrow Conditioning Regimen: 5 people, 12.82%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.26%
High Blood Pressure: 4 people, 10.26%
Urinary Tract Infection: 3 people, 7.69%
Diabetes: 3 people, 7.69%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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