Focalin and Fluconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Focalin (dexmethylphenidate hydrochloride) and Fluconazole (fluconazole). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Focalin and Fluconazole. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Focalin?

Focalin has active ingredients of dexmethylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,781 Focalin users. Check the latest studies of Focalin.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

16 people who take Focalin and Fluconazole together, and have interactions are studied.

Focalin and Fluconazole drug interactions.

What are the common drug interactions of Focalin and Fluconazole, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Hepatic enzyme increased
Hepatitis b
Hypoaesthesia (reduced sense of touch or sensation)
Intestinal obstruction
Muscular weakness (muscle weakness)
Overgrowth bacterial (extra growth due to bacteria)

male:

n/a

What are the common drug interactions of Focalin and Fluconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fatigue (feeling of tiredness)
Gait disturbance
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Hepatic enzyme increased
Hepatitis b
Hypoaesthesia (reduced sense of touch or sensation)
Intestinal obstruction
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)

40-49:

Abdominal abscess (collection of pus in abdomen)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Nausea (feeling of having an urge to vomit)
Vomiting
Surgery

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 50.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 50.00%
Immunodeficiency Common Variable: 5 people, 31.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
Infection: 1 person, 6.25%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 6.25%
Diarrhea: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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