Folic acid and Protamine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Folic acid (folic acid) and Protamine sulfate (protamine sulfate). Common drug interactions include organising pneumonia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Folic acid and Protamine sulfate. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.

What is Protamine sulfate?

Protamine sulfate has active ingredients of protamine sulfate. eHealthMe is studying from 3,292 Protamine sulfate users. Check the latest studies of Protamine sulfate.

On Jul, 15, 2026

39 people who take Folic acid and Protamine sulfate together, and have interactions are studied.

Folic acid and Protamine sulfate drug interactions.

What are the common drug interactions of Folic Acid and Protamine Sulfate, by gender? *:

female:

Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Oropharyngeal pain
Peripheral embolism (sudden interruption of blood flow to an organ or body part)
Peripheral ischaemia (impaired circulation to an extremity)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Pulmonary thrombosis (scarring in the lungs)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)
Respiratory distress (difficulty in breathing)
Secretion discharge

male:

Pain
Renal failure (kidney dysfunction)
Multi-organ failure (multisystem organ failure)
Renal impairment (severely reduced kidney function)
Depression
Blindness
Burning sensation
Colitis ulcerative (inflammation of colon with ulcer)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Folic Acid and Protamine Sulfate, by age (0-1 to 60+)? *:

0-1:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Depression
Fear
Injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain
Renal failure (kidney dysfunction)

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Emotional distress
Fear
Injury
Multi-organ failure (multisystem organ failure)
Pain
Renal failure (kidney dysfunction)

30-39:

n/a

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Memory impairment
Quality of life decreased
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Death
Hypotension (abnormally low blood pressure)
Injury
Multi-organ failure (multisystem organ failure)
Pulmonary hypertension (increase in blood pressure in the lung artery)

50-59:

Renal failure (kidney dysfunction)
Injury
Pain
Anxiety
Fear
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Stress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Burning sensation

60+:

Injury
Pain
Stress
Renal impairment (severely reduced kidney function)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal failure acute (rapid kidney dysfunction)
Anaphylactic reaction (serious allergic reaction)
Depression
Atrioventricular block complete (heart block complete)
Balance disorder

What are the existing conditions these people have? *

Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 10.26%
Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 2 people, 5.13%
Pneumonia: 2 people, 5.13%
Pain: 2 people, 5.13%
Gastric Disorder (disease of stomach): 2 people, 5.13%
Diabetes: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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