Fosamax and Noroxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fosamax (alendronate sodium) and Noroxin (norfloxacin). Common drug interactions include pancreatitis acute among females.

The phase IV clinical study analyzes what interactions people have when they take Fosamax and Noroxin. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.

What is Noroxin?

Noroxin has active ingredients of norfloxacin. It is often used in urinary tract infection. eHealthMe is studying from 1,675 Noroxin users. Check the latest studies of Noroxin.



On Jul, 13, 2026

39 people who take Fosamax and Noroxin together, and have interactions are studied.

Fosamax and Noroxin drug interactions.

What are the common drug interactions of Fosamax and Noroxin, by gender? *:

female:

  1. Pancreatitis acute (sudden inflammation of pancreas)
  2. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  3. Platelet count decreased
  4. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  5. White blood cell count decreased
  6. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  7. Blood creatinine increased
  8. Bradycardia (abnormally slow heart action)
  9. Hypokalaemia (low potassium)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

male:

n/a

What are the common drug interactions of Fosamax and Noroxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pancreatitis acute (sudden inflammation of pancreas)
  2. Hepatitis (inflammation of the liver)
  3. Cytolytic hepatitis (dissolution or destruction of a liver cell)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

30-39:

n/a

40-49:

  1. Adverse event
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Arthropathy
  5. Back pain
  6. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  7. Breast disorder
  8. Dental caries
  9. Depression
  10. Drug hypersensitivity

50-59:

  1. Mean platelet volume decreased (less than normal average size of platelet cells in blood)
  2. Oedema peripheral (superficial swelling)
  3. Platelet count decreased
  4. White blood cell count decreased
  5. Colitis ulcerative (inflammation of colon with ulcer)
  6. Depression
  7. Inflammatory bowel disease
  8. Injury

60+:

  1. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  2. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Loss of consciousness
  5. Renal impairment (severely reduced kidney function)
  6. Conjunctivitis (pink eye)
  7. Erythema (redness of the skin)
  8. Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
  9. Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth)
  10. Abdominal distension

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 15.38%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 10.26%
  3. Gout (uric acid crystals building up in the body): 3 people, 7.69%
  4. Stress And Anxiety: 3 people, 7.69%
  5. Sleep Disorder: 3 people, 7.69%
  6. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 7.69%
  7. Depression: 3 people, 7.69%
  8. Pain: 3 people, 7.69%
  9. Nausea (feeling of having an urge to vomit): 3 people, 7.69%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fosamax and Noroxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fosamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Noroxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fosamax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Noroxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium and norfloxacin (the active ingredients of Fosamax and Noroxin, respectively), and Fosamax and Noroxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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