Frova and Metaxalone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Frova (frovatriptan succinate) and Metaxalone (metaxalone). Common drug interactions include chronic kidney disease among females.

The phase IV clinical study analyzes what interactions people have when they take Frova and Metaxalone. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

On Jul, 10, 2026

15 people who take Frova and Metaxalone together, and have interactions are studied.

What are the common drug interactions of Frova and Metaxalone, by gender? *:

female:

Chronic kidney disease
Cough
Hypovolaemia (a decreased volume of circulating blood in the body)
Neuropathy peripheral (surface nerve damage)
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Renal failure (kidney dysfunction)
Thirst
Cartilage injury
Cystitis (inflammation of the wall of the bladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

n/a

What are the common drug interactions of Frova and Metaxalone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cartilage injury
Disability
Psychiatric symptom
Cough
Dry eye (lack of adequate tears)
Head discomfort
Sinusitis (inflammation of sinus)
Drug hypersensitivity

30-39:

n/a

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Cystitis (inflammation of the wall of the bladder)
Drug hypersensitivity

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 40.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
Neuropathy Peripheral (surface nerve damage): 2 people, 13.33%
Multiple Allergies (allergy to multiple agents): 2 people, 13.33%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Depression: 2 people, 13.33%
Asthma: 2 people, 13.33%
Erythema Multiforme (a type of hypersensitivity reaction): 1 person, 6.67%
Dysmenorrhea (painful menstruation): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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