Glimepiride and Metaxalone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glimepiride (glimepiride) and Metaxalone (metaxalone). Common drug interactions include tubulointerstitial nephritis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Glimepiride and Metaxalone. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Glimepiride?

Glimepiride has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 45,909 Glimepiride users. Check the latest studies of Glimepiride.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

On Jul, 09, 2026

57 people who take Glimepiride and Metaxalone together, and have interactions are studied.

Glimepiride and Metaxalone drug interactions.

What are the common drug interactions of Glimepiride and Metaxalone, by gender? *:

female:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Vaginal haemorrhage (vaginal bleeding)
Vomiting
Weight decreased
Pneumonia
Infection
Herpes ophthalmic (eye infection caused by herpes simplex virus (hsv))
Herpes zoster
Weight increased
Rash

male:

Chronic kidney disease
Hepatic enzyme increased
Abnormal behaviour
Alanine aminotransferase increased
Anxiety
Aspartate aminotransferase increased
Asthenia (weakness)
Asthma
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Constipation

What are the common drug interactions of Glimepiride and Metaxalone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hepatic enzyme increased
Alanine aminotransferase increased
Aspartate aminotransferase increased
B-cell lymphoma stage iv (blood cancer affecting b cells stage iv)
Chronic kidney disease
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Alopecia (absence of hair from areas of the body)

60+:

Infection
Urinary tract infection
Incisional hernia (hernia caused by an incompletely-healed surgical wound)
Osteoporosis (bones weak and more likely to break)
Rash
Blood glucose decreased
Blood pressure increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 15.79%
Pain: 9 people, 15.79%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 15.79%
High Blood Cholesterol: 7 people, 12.28%
High Blood Pressure: 6 people, 10.53%
Hypersensitivity: 5 people, 8.77%
Sleep Disorder: 5 people, 8.77%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 8.77%
Infection: 4 people, 7.02%
Immunodeficiency Common Variable: 4 people, 7.02%

* Approximation only. Some reports may have incomplete information.

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