Glipizide and Nitrofurantoin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glipizide (glipizide) and Nitrofurantoin (nitrofurantoin, macrocrystalline). Common drug interactions include confusional state among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Glipizide and Nitrofurantoin. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

On Jul, 13, 2026

66 people who take Glipizide and Nitrofurantoin together, and have interactions are studied.

Glipizide and Nitrofurantoin drug interactions.

What are the common drug interactions of Glipizide and Nitrofurantoin, by gender? *:

female:

Confusional state
Arthralgia (joint pain)
Asthenia (weakness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Cataract (clouding of the lens inside the eye)
Emotional distress

male:

Anxiety
Pain
Fatigue (feeling of tiredness)
Hydrocele
Hypoaesthesia (reduced sense of touch or sensation)
Injury
Multiple injuries
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myopathy (a muscular disease in which the muscle fibres do not function)
Orchitis (inflammation of the testes)

What are the common drug interactions of Glipizide and Nitrofurantoin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Vomiting
Chest discomfort
Chest pain
Abdominal pain
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)

50-59:

Hypoaesthesia (reduced sense of touch or sensation)
Multiple injuries
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Orchitis (inflammation of the testes)
Organic erectile dysfunction (inability to achieve or maintain an erection long enough to engage in sexual intercourse)
Prostate cancer
Prostatitis (inflammation of the prostate gland)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Blood glucose increased
Chest discomfort

60+:

Pain
Anxiety
International normalised ratio increased
Pelvic abscess
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Emotional distress
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Mobility decreased (ability to move is reduced)
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Anaemia (lack of blood)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 15.15%
Heart Rate Irregular: 5 people, 7.58%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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