Harvoni and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Harvoni (ledipasvir; sofosbuvir) and Abilify (aripiprazole). Common drug interactions include electrolyte imbalance among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Harvoni and Abilify. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Harvoni?

Harvoni has active ingredients of ledipasvir; sofosbuvir. eHealthMe is studying from 19,858 Harvoni users. Check the latest studies of Harvoni.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,455 Abilify users. Check the latest studies of Abilify.

On Aug, 09, 2026

26 people who take Harvoni and Abilify together, and have interactions are studied.

What are the common drug interactions of Harvoni and Abilify, by gender? *:

female:

Electrolyte imbalance
Essential hypertension (primary hypertension)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lymphoedema (localized fluid retention and tissue swelling)
Magnesium metabolism disorder (disease of magnesium utilization)
Obesity (having too much body fat)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)

male:

Pain
Abdominal infection
Blood cholesterol decreased
Blood creatinine decreased
Blood glucose increased
Blood potassium decreased
Blood testosterone decreased
Blood triglycerides increased
Blood urea increased
Blood urea nitrogen/creatinine ratio increased

What are the common drug interactions of Harvoni and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alanine aminotransferase increased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Aspartate aminotransferase increased
Blood calcium decreased
Blood cholesterol decreased
Blood creatinine decreased
Blood glucose increased
Blood potassium decreased
Blood testosterone decreased
Blood triglycerides increased

50-59:

Acute respiratory failure
Adverse drug reaction
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood hyposmosis
Body mass index increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomyopathy (weakening of the heart muscle)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Electrolyte imbalance
Essential hypertension (primary hypertension)

60+:

Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)
Transient global amnesia (a temporary short-term memory loss)

What are the existing conditions these people have? *

Hepatitis C: 11 people, 42.31%
Hiv Infection: 3 people, 11.54%
Headache (pain in head): 3 people, 11.54%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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