Hydralazine hydrochloride and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydralazine hydrochloride (hydralazine hydrochloride) and Morphine (morphine sulfate). Common drug interactions include oculogyric crisis among females and rhabdomyolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Hydralazine hydrochloride and Morphine. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Hydralazine hydrochloride?

Hydralazine hydrochloride has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,238 Hydralazine hydrochloride users. Check the latest studies of Hydralazine hydrochloride.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.



On Jul, 20, 2026

18 people who take Hydralazine hydrochloride and Morphine together, and have interactions are studied.

Hydralazine hydrochloride and Morphine drug interactions.

What are the common drug interactions of Hydralazine Hydrochloride and Morphine, by gender? *:

female:

  1. Oculogyric crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction)
  2. Renal failure (kidney dysfunction)
  3. Respiratory disorder (respiratory disease)
  4. Urinary tract infection
  5. Cardiac failure congestive
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  10. Renal tubular necrosis (death of kidney tubules)

male:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  2. Disease progression
  3. Renal neoplasm (kidney tumour)

What are the common drug interactions of Hydralazine Hydrochloride and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Oculogyric crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

50-59:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Herpes simplex (herpes simplex is a common viral infection)
  3. Small intestinal obstruction (blockage in small intestine)
  4. Chronic kidney disease
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Renal failure (kidney dysfunction)

60+:

  1. Acute respiratory failure
  2. Blood glucose decreased
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Renal failure (kidney dysfunction)
  5. Renal neoplasm (kidney tumour)
  6. Renal tubular necrosis (death of kidney tubules)
  7. Systemic candida (whole body fungal infection)
  8. Cough
  9. Respiratory disorder (respiratory disease)
  10. Urinary tract infection

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 33.33%
  2. Lower Respiratory Tract Infection: 6 people, 33.33%
  3. Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 6 people, 33.33%
  4. Sedation: 5 people, 27.78%
  5. Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 22.22%
  6. Stress And Anxiety: 4 people, 22.22%
  7. Blood Glucose Decreased: 4 people, 22.22%
  8. Blood Glucose Increased: 4 people, 22.22%
  9. Blood Iron Decreased: 4 people, 22.22%
  10. Blood Phosphorus Decreased: 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydralazine hydrochloride and Morphine:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydralazine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydralazine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydralazine hydrochloride and morphine sulfate (the active ingredients of Hydralazine hydrochloride and Morphine, respectively), and Hydralazine hydrochloride and Morphine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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