Hydrocortisone and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Astelin (azelastine hydrochloride). Common drug interactions include fatigue among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Astelin. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

On Jul, 27, 2026

40 people who take Hydrocortisone and Astelin together, and have interactions are studied.

Hydrocortisone and Astelin drug interactions.

What are the common drug interactions of Hydrocortisone and Astelin, by gender? *:

female:

Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pain in extremity
Spinal osteoarthritis (joint cartilage loss in spine)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal pain upper
Anxiety
Dizziness
Injury
Osteonecrosis of jaw (death of bone of jaw)

male:

Pain
Arthralgia (joint pain)
Abscess (pus)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cataract (clouding of the lens inside the eye)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Deafness
Dental caries

What are the common drug interactions of Hydrocortisone and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Erythema (redness of the skin)
Staphylococcal bacteraemia (a bacterial infection of blood)
Swelling
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Pain
Pyrexia (fever)
Wound

10-19:

n/a

20-29:

Diarrhoea
Abdominal pain
Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Dyspepsia (indigestion)
Eye swelling
Furuncle (infection of the hair follicle)
Hypertension (high blood pressure)

30-39:

Anaphylactic reaction (serious allergic reaction)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

40-49:

Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Arthralgia (joint pain)
Bone pain
Chest pain
Exposed bone in jaw
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Inflammation
Intervertebral disc degeneration (spinal disc degeneration)
Metastases to bone (cancer spreads to bone)

50-59:

Abdominal pain upper
Balance disorder
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Fatigue (feeling of tiredness)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Mood altered (changes in mood)
Muscle spasms (muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)

60+:

Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Impaired gastric emptying
Muscle spasms (muscle contraction)
Neoplasm malignant (cancer tumour)
Arthralgia (joint pain)
Bradycardia (abnormally slow heart action)
Cardiac failure congestive
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Pain: 12 people, 30.00%
Osteoporosis (bones weak and more likely to break): 10 people, 25.00%
Asthma: 8 people, 20.00%
High Blood Pressure: 6 people, 15.00%
Stress And Anxiety: 6 people, 15.00%
Metastasis (spreadable cancer to other organ from origin): 5 people, 12.50%
Depression: 4 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.00%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 10.00%
Insomnia (sleeplessness): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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