Hydrocortone and Lasix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortone (hydrocortisone acetate) and Lasix (furosemide). Common drug interactions include blood bilirubin increased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortone and Lasix. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortone?

Hydrocortone has active ingredients of hydrocortisone acetate. It is often used in pain. eHealthMe is studying from 912 Hydrocortone users. Check the latest studies of Hydrocortone.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.



On Jul, 26, 2026

39 people who take Hydrocortone and Lasix together, and have interactions are studied.

Hydrocortone and Lasix drug interactions.

What are the common drug interactions of Hydrocortone and Lasix, by gender? *:

female:

  1. Blood bilirubin increased
  2. Blood potassium decreased
  3. Cardiac arrest
  4. Cardiac failure
  5. Platelet count decreased
  6. Renal failure (kidney dysfunction)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  9. Hemiplegia (paralysis of one side of the body)
  10. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

male:

  1. Pneumonia
  2. Anaemia (lack of blood)
  3. Pleural effusion (water on the lungs)
  4. Acute respiratory distress syndrome
  5. Blast cell count increased
  6. Blood lactate dehydrogenase increased
  7. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  8. Diarrhoea
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the common drug interactions of Hydrocortone and Lasix, by age (0-1 to 60+)? *:

0-1:

  1. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  2. Drug ineffective
  3. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
  4. Venoocclusive disease (small veins in the liver are obstructed)

2-9:

  1. Urine output decreased
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Herpes zoster
  4. Skin infection
  5. Stomatitis (inflammation of mucous membrane of mouth)

10-19:

n/a

20-29:

  1. Encephalitis viral (inflammation of the brain due to viral infection)

30-39:

n/a

40-49:

  1. Aspartate aminotransferase increased
  2. Blood creatinine increased
  3. Blood pressure decreased
  4. C-reactive protein increased
  5. Erythema (redness of the skin)
  6. Erythema multiforme (a type of hypersensitivity reaction)
  7. Generalised erythema (redness of the skin all over the body)
  8. Lip erosion (peeling off of lip)
  9. Multi-organ failure (multisystem organ failure)
  10. Nikolsky's sign

50-59:

  1. Blood glucose increased
  2. Blood lactate dehydrogenase increased
  3. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  4. Constipation
  5. Diarrhoea
  6. Disease progression
  7. Flushing (the warm, red condition of human skin)
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

60+:

  1. Pneumonia
  2. Anaemia (lack of blood)
  3. Fibrin degradation products increased
  4. Multi-organ failure (multisystem organ failure)
  5. Nausea (feeling of having an urge to vomit)
  6. Septic shock (shock due to blood infection)
  7. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  8. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  9. White blood cell count decreased
  10. Adrenal cortex necrosis (death adrenal cortex tissue)

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 10 people, 25.64%
  2. Infection: 6 people, 15.38%
  3. Insomnia (sleeplessness): 5 people, 12.82%
  4. Sedation: 4 people, 10.26%
  5. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 10.26%
  6. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 4 people, 10.26%
  7. Urine Output Decreased: 3 people, 7.69%
  8. Conjunctivitis (pink eye): 3 people, 7.69%
  9. Constipation: 3 people, 7.69%
  10. Cytomegalovirus Infection: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortone and Lasix?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrocortone and Lasix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lasix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocortone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lasix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone acetate and furosemide (the active ingredients of Hydrocortone and Lasix, respectively), and Hydrocortone and Lasix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: